Parker G, Hadzi-Pavlovic D, Boyce P
Mood Disorders Unit (University of New South Wales), Prince Henry Hospital, Sydney.
Aust N Z J Psychiatry. 1989 Sep;23(3):357-68. doi: 10.3109/00048678909068293.
We review the concept of endogenous depression historically and undertake quantitative analyses of representative factor analytic studies. We also report an empirical study, isolating symptoms and signs associated with a clinical diagnosis of psychotic/endogenous depression, made by a large number of clinical raters assessing 300 depressives. The quantitative analyses and the study of practising psychiatrists agreed in delineating depressive type and together suggest a more restricted construct of endogenous and psychotic depression than has been held historically. Key clinical features isolated were severity, retardation, delusions and paranoid features, non-reactivity and non-variability in mood, while vegetative features appeared to lack relevance.
我们从历史角度回顾内源性抑郁症的概念，并对具有代表性的因素分析研究进行定量分析。我们还报告了一项实证研究，该研究由大量临床评估人员对300名抑郁症患者进行评估，分离出与精神病性/内源性抑郁症临床诊断相关的症状和体征。定量分析与执业精神科医生的研究在抑郁症类型的界定上达成一致，共同表明内源性和精神病性抑郁症的概念比历史上所认为的更为局限。分离出的关键临床特征包括严重程度、迟缓、妄想和偏执特征、情绪无反应性和无变化性，而躯体症状似乎不相关。
