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伊朗首都德黑兰的(双翅目:蚊科)对杀虫剂具有高度抗性

High Insecticides Resistance in (Diptera: Culicidae) from Tehran, Capital of Iran.

作者信息

Salim-Abadi Yaser, Oshaghi Mohammad Ali, Enayati Ahmad Ali, Abai Mohammad Reza, Vatandoost Hassan, Eshraghian Mohammad Reza, Mirhendi Hossein, Hanafi-Bojd Ahmad Ali, Gorouhi Mohammad Amin, Rafi Fatemeh

机构信息

Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

School of Public Health and Health Sciences Research Centre, Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

J Arthropod Borne Dis. 2016 Oct 4;10(4):483-492. eCollection 2016 Dec.

Abstract

BACKGROUND

During recent years transmission of (dog heart worm) by and West Nile virus have been reported from Iran. The present study was preformed for evaluating the susceptibility status of collected from capital city of Tehran, Iran.

METHODS

Four Insecticides including: DDT 4%, Lambdacyhalothrin 0.05%, Deltamethrin 0.05% and Cyfluthrin 0.15 % according to WHO standard methods were used for evaluating the susceptibility status of from Tehran moreover For comparison susceptibility status a Laboratory strain also was used. Bioassay data were analyzed using Probit program. The lethal time for 50% and 90% mortality (LT and LT) values were calculated from regression line.

RESULTS

The susceptibility status of lab strain of revealed that it is susceptible to Lambdacyhalothrin, Deltamethrin, Cyfluthrin and resistant to DDT. Moreover cyfluthrin with LT=36 seconds and DDT with LT=3005 seconds had the least and most LTs. Field population was resistance to all tested insecticides and DDT yielded no mortality.

CONCLUSION

Highly resistance level against all WHO recommended imagicides were detected in field populations. We suggest more biochemical and molecular investigations to detect resistance mechanisms in the field population for further decision of vector control.

摘要

背景

近年来,伊朗已报告由[某种蚊子]传播犬心丝虫以及西尼罗河病毒。本研究旨在评估从伊朗首都德黑兰采集的[某种蚊子]的易感性状况。

方法

根据世界卫生组织标准方法,使用四种杀虫剂,包括4%的滴滴涕、0.05%的高效氯氟氰菊酯、0.05%的溴氰菊酯和0.15%的氟氯氰菊酯,来评估德黑兰[某种蚊子]的易感性状况。此外,为了比较易感性状况,还使用了一个实验室品系。生物测定数据使用Probit程序进行分析。从回归线计算出50%和90%死亡率的致死时间(LT50和LT90)值。

结果

[某种蚊子]实验室品系的易感性状况表明,它对高效氯氟氰菊酯、溴氰菊酯、氟氯氰菊酯敏感,对滴滴涕耐药。此外,氟氯氰菊酯的LT50 = 36秒,滴滴涕的LT50 = 3005秒,分别具有最短和最长的LT50。野外种群对所有测试杀虫剂均耐药,滴滴涕未导致死亡。

结论

在野外种群中检测到对世界卫生组织推荐的所有杀成虫剂具有高度耐药性。我们建议进行更多的生化和分子研究,以检测野外种群中的耐药机制,以便进一步做出病媒控制决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab2/5186738/0a69ee8a2d93/JAD-10-483-g001.jpg

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