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Porcine diazepam-binding inhibitor and bovine diazepam-binding inhibitor affect morphine antinociception via different receptors.

作者信息

Chen Yu-Zhen, Li Xiao-Cun, Guo Zhen-Quan, Zhou Li, Zhou Zhuan, Liang Song-Ping, Wu Cai-Hong

机构信息

State Key Laboratory of Membrane Biology, Peking University, Beijing, 100871, China.

Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, 100029, China.

出版信息

Protein Cell. 2017 Feb;8(2):140-143. doi: 10.1007/s13238-016-0355-5.

DOI:10.1007/s13238-016-0355-5
PMID:28032250
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5291778/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ae/5291778/fdd0f2fbc3b0/13238_2016_355_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ae/5291778/0d5e8e3f3564/13238_2016_355_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ae/5291778/fdd0f2fbc3b0/13238_2016_355_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ae/5291778/0d5e8e3f3564/13238_2016_355_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ae/5291778/fdd0f2fbc3b0/13238_2016_355_Fig2_HTML.jpg

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Porcine diazepam-binding inhibitor and bovine diazepam-binding inhibitor affect morphine antinociception via different receptors.猪地西泮结合抑制剂和牛地西泮结合抑制剂通过不同受体影响吗啡镇痛作用。
Protein Cell. 2017 Feb;8(2):140-143. doi: 10.1007/s13238-016-0355-5.
2
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本文引用的文献

1
Up-regulated L-type high voltage-gated calcium channels cause increase in diazepam binding inhibitor induced by sustained morphine exposure in mouse cerebrocortical neurons.上调的L型高电压门控钙通道导致小鼠大脑皮质神经元中持续吗啡暴露诱导的地西泮结合抑制剂增加。
Life Sci. 2006 Dec 14;80(2):166-72. doi: 10.1016/j.lfs.2006.08.036. Epub 2006 Sep 12.
2
Continuous treatment with morphine increases diazepam binding inhibitor mRNA in mouse brain.吗啡持续治疗可增加小鼠大脑中地西泮结合抑制剂的信使核糖核酸。
J Neurochem. 1998 Dec;71(6):2638-41. doi: 10.1046/j.1471-4159.1998.71062638.x.
3
Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.
一种对苯二氮䓬受体具有激动作用的内源性多肽的分离、特性鉴定及纯化至均一性。
Proc Natl Acad Sci U S A. 1983 Jun;80(11):3531-5. doi: 10.1073/pnas.80.11.3531.
4
Isolation and characterization of porcine diazepam-binding inhibitor, a polypeptide not only of cerebral occurrence but also common in intestinal tissues and with effects on regulation of insulin release.猪地西泮结合抑制剂的分离与鉴定，一种不仅存在于大脑中，在肠道组织中也普遍存在且对胰岛素释放调节有作用的多肽。
Eur J Biochem. 1988 Jun 1;174(2):239-45. doi: 10.1111/j.1432-1033.1988.tb14088.x.
5
The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.
J Biol Chem. 1986 Jan 15;261(2):576-83.
6
Bovine endozepine potentiates morphine analgesia in mice.牛内啡肽增强小鼠吗啡镇痛作用。
Life Sci. 1991;48(17):PL79-83. doi: 10.1016/0024-3205(91)90129-y.
7
Diazepam binding inhibitor (DBI): a peptide with multiple biological actions.地西泮结合抑制剂（DBI）：一种具有多种生物学作用的肽。
Life Sci. 1991;49(5):325-44. doi: 10.1016/0024-3205(91)90440-m.