Rodríguez Amílcar G, Sánchez Jorge L, Sánchez Julio E
*Department of Dermatology, School of Medicine, University of Puerto Rico, San Juan, PR; and †Department of Dermatology, University of Puerto Rico, San Juan, PR.
Am J Dermatopathol. 2017 Feb;39(2):e26-e28. doi: 10.1097/DAD.0000000000000722.
Granuloma annulare (GA) is a common, asymptomatic dermatosis of unknown etiology. Many variants exist, among them widespread papules, papules in photodistribution, papules marked by tiny crusts ("perforating" GA), patches, plaques, and nodules (subcutaneous GA). The histopathological hallmark is a palisaded histiocytic infiltrate surrounding a central area of degenerated collagen with abundant mucin deposits. We report 2 women who presented with persistent nodules on the nose, which, on histopathological examination, showed a palisaded granuloma. We propose that these cases represent an unusual variant of GA occurring on the nose.
环状肉芽肿（GA）是一种常见的、病因不明的无症状性皮肤病。它有多种变体，包括泛发性丘疹、光暴露部位的丘疹、有微小痂皮的丘疹（“穿通性”GA）、斑片、斑块和结节（皮下GA）。组织病理学特征是栅栏状组织细胞浸润围绕着中央区变性的胶原，伴有大量黏蛋白沉积。我们报告了2例女性患者，她们的鼻子上出现了持续性结节，经组织病理学检查显示为栅栏状肉芽肿。我们认为这些病例代表了发生在鼻子上的一种不寻常的GA变体。
