斑块状环状肉芽肿：6例患者的临床病理研究
Patch granuloma annulare: clinicopathologic study of 6 patients.
作者信息
Mutasim D F, Bridges A G
机构信息
Department of Dermatology, University of Cincinnati Medical Center, Ohio, USA.
出版信息
J Am Acad Dermatol. 2000 Mar;42(3):417-21. doi: 10.1016/s0190-9622(00)90212-3.
BACKGROUND
Granuloma annulare is a common skin disorder that usually presents with smooth papules arranged as annular plaques. Variants, such as disseminated, subcutaneous, and perforating granuloma annulare, have been described.
OBJECTIVE
The purpose of this study is to describe the clinical and histologic features of a distinct patch form of granuloma annulare.
METHODS
The clinical and histologic features of 6 patients with patch granuloma annulare were evaluated.
RESULTS
Six women 27 to 72 years of age had patches on the extremities. Two patients also had a lesion on the trunk. Only one patient had annular patches. Histologic examination showed an interstitial infiltrate of lymphocytes and histiocytes with diffuse necrobiosis.
CONCLUSION
Patch granuloma annulare is a distinct variant with rather subtle clinical and histologic features. A high index of suspicion both clinically and histologically aids in making the diagnosis.
背景
环状肉芽肿是一种常见的皮肤疾病，通常表现为排列成环状斑块的光滑丘疹。已描述了多种变体，如播散性、皮下和穿通性环状肉芽肿。
目的
本研究的目的是描述一种独特的斑块型环状肉芽肿的临床和组织学特征。
方法
对6例斑块型环状肉芽肿患者的临床和组织学特征进行评估。
结果
6名年龄在27至72岁之间的女性在四肢出现斑块。2名患者躯干也有病变。只有1名患者有环状斑块。组织学检查显示淋巴细胞和组织细胞间质浸润伴弥漫性渐进性坏死。
结论
斑块型环状肉芽肿是一种具有相当微妙临床和组织学特征的独特变体。临床和组织学上的高度怀疑有助于做出诊断。
Zotero 插件