From the *Department of Nuclear Medicine and Clinical Cancer Research Center, Aalborg University Hospital, Aalborg; and †Department of Clinical Medicine, Aalborg University, Aalborg; ‡Department of Urology, Regional Hospital West Jutland, Holstebro, Denmark; and §Department of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Clin Nucl Med. 2017 Mar;42(3):221-222. doi: 10.1097/RLU.0000000000001522.
Ga-PSMA PET/CT is increasingly used to assess prostate cancer. Avid Ga-PSMA uptake by thyroid cancer and renal cell carcinoma (RCC) has been reported in few cases. A 75-year-old man who received a diagnosis of RCC in 2006 and prostate cancer in 2009 presented with elevated prostate-specific antigen levels (0.7 ng/mL) following prostatectomy. Ga-PSMA PET/CT showed avid Ga-PSMA uptake in 1 pelvic and 1 retroperitoneal lymph node and focal Ga-PSMA accumulation in the thyroid. Excised retroperitoneal lymph node and thyroid tissues showed metastases from RCC, whereas the pelvic lymph node exhibited metastasis from prostate cancer.
镓-PSMA PET/CT 正越来越多地用于评估前列腺癌。在少数病例中，曾报道过甲状腺癌和肾细胞癌（RCC）摄取镓-PSMA 明显增加的情况。一位 75 岁男性，2006 年被诊断为 RCC，2009 年被诊断为前列腺癌，前列腺切除术后前列腺特异性抗原水平升高（0.7ng/mL）。镓-PSMA PET/CT 显示 1 个骨盆和 1 个腹膜后淋巴结摄取 Ga-PSMA 明显增加，甲状腺局灶性 Ga-PSMA 聚集。切除的腹膜后淋巴结和甲状腺组织显示 RCC 转移，而骨盆淋巴结显示前列腺癌转移。
