Sharpe N G, Isenberg D, Williams D G, Latchman D S
Department of Biochemistry, University College, Middlesex School of Medicine, London, UK.
J Autoimmun. 1989 Oct;2(5):701-8. doi: 10.1016/s0896-8411(89)80008-3.
Three Sm proteins, B, B' and D, which are highly immunoreactive in systemic lupus erythematosus (SLE), increase in abundance in Vero cells infected with laboratory strains and clinical isolates of herpes simplex virus (HSV) types 1 and 2. The autoimmune antigen La (SS-B) does not accumulate in identical infections. The significance of the Sm antigen accumulation is discussed in terms of its possible role in HSV infection and in connection with the origin of autoantibodies in SLE.
