Elevation of the levels of SmB, B' and D proteins but not that of the La (SS-B) antigen during HSV infections.
作者信息
Sharpe N G, Isenberg D, Williams D G, Latchman D S
机构信息
Department of Biochemistry, University College, Middlesex School of Medicine, London, UK.
出版信息
J Autoimmun. 1989 Oct;2(5):701-8. doi: 10.1016/s0896-8411(89)80008-3.
PMID:2803478
Abstract
Three Sm proteins, B, B' and D, which are highly immunoreactive in systemic lupus erythematosus (SLE), increase in abundance in Vero cells infected with laboratory strains and clinical isolates of herpes simplex virus (HSV) types 1 and 2. The autoimmune antigen La (SS-B) does not accumulate in identical infections. The significance of the Sm antigen accumulation is discussed in terms of its possible role in HSV infection and in connection with the origin of autoantibodies in SLE.
摘要
Zotero 插件