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克罗地亚青少年的药物医疗用途、处方药的非医疗用途及风险行为

Medical use, nonmedical use of prescription medication and risk behaviour among Croatian adolescents.

作者信息

Kuzman Marina, Posavec Marija

机构信息

Andrija Stampar Teaching Institute of Public Health, Mirogojska 16, 10000 Zagreb, Croatia,

出版信息

Psychiatr Danub. 2016 Dec;28 Suppl 2:223-233.

Abstract

BACKGROUND

At the drug scene some major shifts were observed, more and more reports highlighted the abuse of prescription medication. Despite the importance of controlled medication in treatment child and adolescent disorders, this increase may be a factor which influence misuse and nonmedical use of prescribed drugs among adolescents.

SUBJECT AND METHODS

Croatian data from ESPAD survey in 2003, 2007 and 2011 were used, and variables selected from the international ESPAD questionnaire. Dependent variable was taking tranquilizers or sedatives prescribed by doctor in the past 12 months. Independent variables were nonmedical use of tranquilizers/sedatives, use of other psychoactive substances, school performance, truancy, delinquent behaviour, satisfaction with relationships with parents, friends, health, self-perception, financial situation and symptoms of depression. The respondents were 8849 students (4393 boys and 4456 girls) in three consecutive ESPAD surveys (2003, 2007 and 2011).

RESULTS

In multivariate analysis for all three survey years the strongest predictor for prescription medication use was use of sedatives/tranquilizers without prescription (OR 6.14; CI 4.08-9.23; OR 8.16; CI4.65-14.32; OR 9.77; CI5.92-15.13). Frequent drinking and excessive drinking or drunkenness also predicted prescription medication use, (OR 1.85; CI1.10-3.10; OR 2.01: CI 1.20-3.39). Among other problem behaviours lower school performance (OR 2.92; CI 1.41-6.05; OR 2.56; CI 1.12-5.87), missed school days OR 1.59; OR1.01-2.51; OR1.72; CI 1.03-2.87), aggressive behaviour (OR 1.532; CI 1.01-2.28; OR1.65; CI 1.04-2.62), depressive symptoms (OR 2.19; CI 1.24-3.85) and poorer financial situation were connected with prescription medication use.

CONCLUSION

Prescription use of tranquilizers/sedatives was predicted by nonmedical tranquilizers/sedatives use, alcohol abuse, symptoms of depression and variables indicating maladjusted behaviour. Although there is sufficient evidence that prescription medication abuse might went unobserved, the further analysis which could better explain its' role and impact is still needed.

摘要

背景

在毒品领域观察到了一些重大变化,越来越多的报告强调了处方药的滥用情况。尽管管控药物在治疗儿童和青少年疾病方面很重要,但这种增加可能是影响青少年滥用和非医疗使用处方药的一个因素。

对象与方法

使用了2003年、2007年和2011年克罗地亚ESPAD调查的数据,并从国际ESPAD问卷中选取变量。因变量是在过去12个月内服用医生开的镇静剂或安眠药。自变量是非医疗使用镇静剂/安眠药、使用其他精神活性物质、学业成绩、逃学、违法行为、对与父母、朋友关系的满意度、健康状况、自我认知、财务状况和抑郁症状。受访者是连续三次ESPAD调查(2003年、2007年和2011年)中的8849名学生(4393名男生和4456名女生)。

结果

在对所有三个调查年份的多变量分析中,使用处方药的最强预测因素是无处方使用镇静剂/安眠药(OR 6.14;CI 4.08 - 9.23;OR 8.16;CI 4.65 - 14.32;OR 9.77;CI 5.92 - 15.13)。频繁饮酒和过度饮酒或醉酒也预测了处方药的使用(OR 1.85;CI 1.10 - 3.10;OR 2.01:CI 1.20 - 3.39)。在其他问题行为中,学业成绩较低(OR 2.92;CI 1.41 - 6.05;OR 2.56;CI 1.12 - 5.87)、缺课天数(OR 1.59;OR 1.01 - 2.51;OR 1.72;CI 1.03 - 2.87)、攻击性行为(OR 1.532;CI 1.01 - 2.28;OR 1.65;CI 1.04 - 2.62)、抑郁症状(OR 2.19;CI 1.24 - 3.85)和较差的财务状况与处方药的使用有关。

结论

非医疗使用镇静剂/安眠药、酗酒、抑郁症状以及表明行为失调的变量可预测镇静剂/安眠药的处方使用情况。尽管有充分证据表明处方药滥用可能未被察觉,但仍需要进一步分析以更好地解释其作用和影响。

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