Departamento de Psicobiologia, Universidade Federal de São Paulo, Rua Botucatu, 862- 1° andar, São Paulo CEP 04023-062, Brasil.
BMC Public Health. 2013 May 24;13:499. doi: 10.1186/1471-2458-13-499.
Although the nonprescribed use of tranquilizers or sedatives by adolescents is a cause for concern in many countries, there is a shortage of data from low and middle income countries (LAMIC). The present study aims to estimate the prevalence of nonprescribed use of tranquilizers/sedatives by adolescents in Brazil, and to assess how socioeconomic and demographic circumstances, as well as indicators of access to these substances are associated with their use and with risk perception.
A cross-sectional study was conducted using a multi-stage probability sample of 18131 high school students from public and private schools from all 27 Brazilian state capitals. A self-reporting questionnaire was used to obtain information on social and economic circumstances, nonprescribed use of tranquilizers or sedatives and risk perception of their use.
Lifetime nonprescribed use of tranquilizers or sedatives was reported by 5% of respondents, more commonly among females (OR: 2.19, 95% CI: 1.75-2.75) and those attending private schools (OR: 1.47, 95% CI: 1.17-1.84). The use of tranquilizers/sedatives by relatives or friends was associated with nonprescribed use by the participant (OR: 4.26, 95% CI: 3.46-5.23) and a majority of lifetime users obtained these substances from a family environment (82%). Previous medical prescription was independently associated with nonprescribed use (OR: 6.61, 95% CI: 4.87-8.98) and with low risk perception (OR: 2.42, 95% CI: 1.12-5.24).
A substantial proportion of Brazilian adolescents use nonprescribed tranquilizers/sedatives. Easy access to these substances seems to play an important role in this use and should be tackled by preventive and treatment interventions.
尽管在许多国家,青少年非处方使用镇静剂或安定类药物引起了关注,但来自中低收入国家(LMIC)的数据却很缺乏。本研究旨在评估巴西青少年非处方使用镇静剂/安定类药物的流行率,并评估社会经济和人口统计学情况,以及获得这些物质的指标与使用和风险认知之间的关系。
使用来自巴西所有 27 个州首府的公立和私立学校的多阶段概率样本对 18131 名高中生进行了横断面研究。使用自我报告问卷获取有关社会和经济情况、非处方使用镇静剂或安定类药物以及对其使用风险的认知的信息。
5%的受访者报告称曾有过非处方使用镇静剂或安定类药物的经历,女性(OR:2.19,95%CI:1.75-2.75)和私立学校学生(OR:1.47,95%CI:1.17-1.84)更为常见。亲戚或朋友使用镇静剂/安定类药物与参与者的非处方使用相关(OR:4.26,95%CI:3.46-5.23),且大多数有过此类药物使用经历的人是从家庭环境中获得这些物质的(82%)。以前的医学处方与非处方使用(OR:6.61,95%CI:4.87-8.98)和低风险认知(OR:2.42,95%CI:1.12-5.24)独立相关。
巴西有相当一部分青少年使用非处方镇静剂/安定类药物。这些物质的获取途径容易似乎在这种使用中起着重要作用,应通过预防和治疗干预措施加以解决。