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颞下颌关节紊乱患者磁共振成像中偶然发现广泛的口咽肿物：一例报告

Incidental finding of an extensive oropharyngeal mass in magnetic resonance imaging of a patient with temporomandibular disorder: A case report.

作者信息

Omolehinwa Temitope T, Mupparapu Mel, Akintoye Sunday O

机构信息

Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Imaging Sci Dent. 2016 Dec;46(4):285-290. doi: 10.5624/isd.2016.46.4.285. Epub 2016 Dec 20.

DOI:10.5624/isd.2016.46.4.285
PMID:28035308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5192028/
Abstract

In this report, we describe the incidental finding of an oropharyngeal mass in a patient who presented with a chief complaint of temporomandibular pain. The patient was initially evaluated by an otorhinolaryngologist for complaints of headaches, earache, and sinus congestion. Due to worsening headaches and trismus, he was further referred for the management of temporomandibular disorder. The clinical evaluation was uneventful except for limited mouth opening (trismus). An advanced radiological evaluation using magnetic resonance imaging revealed a mass in the nasopharyngeal/oropharyngeal region. The mass occupied the masticatory space and extended superioinferiorly from the skull base to the mandible. A diagnostic biopsy of the lesion revealed a long-standing human papilloma virus (HPV-16)-positive squamous cell carcinoma of the oropharynx. This case illustrates the need for the timely radiological evaluation of seemingly innocuous orofacial pain.

摘要

在本报告中，我们描述了一例以颞下颌关节疼痛为主诉的患者偶然发现口咽部肿物的情况。该患者最初因头痛、耳痛和鼻窦充血等症状由耳鼻喉科医生进行评估。由于头痛和牙关紧闭症状加重，他被进一步转诊以治疗颞下颌关节紊乱症。除了张口受限（牙关紧闭）外，临床评估未见异常。使用磁共振成像进行的高级影像学评估显示鼻咽/口咽区域有一个肿物。该肿物占据咀嚼肌间隙，从上颌骨底部至下颌骨呈上下延伸。对该病变进行的诊断性活检显示为一例长期存在的口咽部人乳头瘤病毒（HPV-16）阳性鳞状细胞癌。该病例说明了对于看似无害的口面部疼痛进行及时影像学评估的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/22ee18b40d98/isd-46-285-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/5313d6867fec/isd-46-285-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/f033874caf42/isd-46-285-g006.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/9081dac5edfd/isd-46-285-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/22ee18b40d98/isd-46-285-g009.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/1db231480601/isd-46-285-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/5693205aff24/isd-46-285-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/f033874caf42/isd-46-285-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/ae16fcb02213/isd-46-285-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/9081dac5edfd/isd-46-285-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0426/5192028/22ee18b40d98/isd-46-285-g009.jpg

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本文引用的文献

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The New Face of Head and Neck Cancer: The HPV Epidemic.头颈癌的新面貌：人乳头瘤病毒流行情况
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