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Adenoid cystic carcinoma of the skull base mimicking temporomandibular disorder.

作者信息

Sari-Rieger Aynur, Hassfeld Stefan, Junker Klaus, Rustemeyer Jan

机构信息

Department of Oral and Maxillofacial Surgery, Plastic Operations, Klinikum Bremen-Mitte, School of Medicine of the University of Göttingen, Bremen, Germany.

出版信息

Oral Maxillofac Surg. 2014 Mar;18(1):115-8. doi: 10.1007/s10006-013-0414-5. Epub 2013 May 1.

DOI:10.1007/s10006-013-0414-5
PMID:23636713
Abstract

BACKGROUND

Temporomandibular disorder (TMD) involves problems of the temporomandibular joint and its adjacent muscular system. Because TMD prevalence is high among Western populations, complaints in these regions are generally attributed to TMD. However, in rare cases, TMD symptoms are mimicked by malignant tumors of the head.

CASE REPORT

Upon first presentation, an 18-year-old female complained about typical symptoms of TMD. After an initial splint therapy and physiotherapy, painful symptoms increased significantly. Twelve weeks after initial diagnosis, further diagnostic imaging revealed a tumor formation at the skull base with infiltration of the infratemporal fossa. Histological evaluation confirmed the diagnosis of adenoid cystic carcinoma. Two years after resection of the tumor, lung metastases were detected with no option of curative treatment.

CONCLUSION

TMD symptoms, which are refractory to treatment or exhibit significant worsening during therapy, should be regarded as warning signals and as an indication that early further diagnostic imaging is warranted.

摘要

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本文引用的文献

1
Adenoid cystic carcinoma of the head and neck: Incidence and survival trends based on 1973-2007 Surveillance, Epidemiology, and End Results data.头颈部腺样囊性癌:基于 1973-2007 年监测、流行病学和最终结果数据的发病率和生存趋势。
Cancer. 2012 Sep 15;118(18):4444-51. doi: 10.1002/cncr.27408. Epub 2012 Jan 31.
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Temporomandibular disorders associated with metastases to the temporomandibular joint: a review of the literature and 3 additional cases.与颞下颌关节转移相关的颞下颌关节紊乱病:文献综述及另外3例病例报告
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伪装成颞下颌关节口面部疼痛的鼻咽癌
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4
Simultaneous occurrence of 2 different low-grade malignancies mimicking temporomandibular joint dysfunction.两种不同的低度恶性肿瘤同时发生,酷似颞下颌关节功能障碍。
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Cost-effectiveness of treatments for temporomandibular disorders: biopsychosocial intervention versus treatment as usual.颞下颌关节紊乱症治疗的成本效益:生物心理社会干预与常规治疗对比
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Reactive granulomatous lesion in the pterygomandibular fossa mimicking a temporomandibular disorder.翼下颌窝内的反应性肉芽肿性病变,酷似颞下颌关节紊乱病。
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