Taniguchi Nobukazu
Department of Chemistry, Fukushima Medical University, Fukushima 960-1295, Japan.
J Org Chem. 2015 Aug 7;80(15):7797-802. doi: 10.1021/acs.joc.5b01176. Epub 2015 Jul 17.
Nickel-catalyzed hydroxysulfonylation of alkenes was achieved using sodium sulfinates under air atmosphere. The procedure enabled the selective synthesis of β-hydroxysulfones in good yields and suppressed the formation of β-ketosulfones. On the contrary, sulfonylation of alkynes with sodium sulfonates afforded only β-ketosulfones.
在空气氛围下，使用亚磺酸钠实现了镍催化的烯烃羟基磺酰化反应。该方法能够以良好的产率选择性合成β-羟基砜，并抑制了β-酮砜的形成。相反，炔烃与磺酸钠的磺酰化反应仅生成β-酮砜。
