Felsten G, Thompson M E, Cook J A, Tapp W N, Natelson B H
Primate Neuro-behavioral Unit, VA Medical Center, East Orange, New Jersey.
J Neural Transm Gen Sect. 1989;78(3):271-8. doi: 10.1007/BF01249235.
Nearly 69% of nucleus ambiguus neurons in the anesthetized, artificially respired dog responded to nonpharmacological manipulations of arterial pressure (AP). All were active at resting AP, most responded robustly to increased AP, and of these, about half showed activity modulated by the respiratory cycle. Other AP-sensitive neurons fired only during the inspiratory or expiratory phase of the pump-driven respiratory cycle, and were inhibited by increased AP and excited by decreased AP.
在麻醉且进行人工呼吸的狗中，近69%的疑核神经元对动脉血压（AP）的非药物性操作有反应。所有神经元在静息动脉血压时均有活动，大多数对动脉血压升高有强烈反应，其中约一半的活动受呼吸周期调制。其他对动脉血压敏感的神经元仅在泵驱动呼吸周期的吸气或呼气阶段放电，且被动脉血压升高抑制，被动脉血压降低兴奋。
