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[西班牙儿科学会免疫接种计划:2017年建议]

[Immunisation schedule of the Spanish Association of Paediatrics: 2017 recommendations].

作者信息

Moreno-Pérez David, Álvarez García Francisco José, Arístegui Fernández Javier, Cilleruelo Ortega María José, Corretger Rauet José María, García Sánchez Nuria, Hernández Merino Ángel, Hernández-Sampelayo Matos Teresa, Merino Moína Manuel, Ortigosa Del Castillo Luis, Ruiz-Contreras Jesús

出版信息

An Pediatr (Barc). 2017 Feb;86(2):98.e1-98.e9. doi: 10.1016/j.anpedi.2016.10.009. Epub 2016 Dec 27.

DOI:10.1016/j.anpedi.2016.10.009
PMID:28038948
Abstract

The Advisory Committee on Vaccines of the Spanish Association of Paediatrics (CAV- AEP) annually publishes the immunisation schedule which, in our opinion, is considered optimal for children resident in Spain, taking into account the evidence available on current vaccines. Pneumococcal and varicella immunisation in early childhood is already included in all funded vaccines present in the regional immunisation programmes. Furthermore, this committee establishes recommendations on vaccines not included in official calendars (non-funded immunisations), such as rotavirus, meningococcal B, and meningococcal ACWY. As regards funded immunisations, 2+1 strategy (2, 4, 11-12 months) with hexavalent (DTaP-IPV-Hib-HB) and 13-valent pneumococcal vaccines is recommended. Administration of the 6-year booster dose with DTaP is recommended, as well as a poliomyelitis dose for children who had received the 2+1 scheme, with the Tdap vaccine for adolescents and pregnant women between 27 and 32 weeks gestation. The two-dose scheme should be used for MMR (12 months and 2-4 years) and varicella (15 months and 2-4 years). Coverage of human papillomavirus vaccination in girls aged 12 with a two-dose scheme (0, 6 months) should be improved. Information and recommendations for male adolescents about potential beneficial effects of the tetravalent HPV vaccine should also be provided. ACWY meningococcal vaccine is the optimal choice in adolescents. For recommended unfunded immunisations, the CAV-AEP recommends the administration of meningococcal B vaccine, due to the current availability in Spanish community pharmacies, with a 3+1 scheme. CAV-AEP requests the incorporation of this vaccine in the funded unified schedule. Vaccination against rotavirus is recommended in all infants.

摘要

西班牙儿科学会疫苗咨询委员会(CAV - AEP)每年都会发布免疫规划时间表。我们认为,该时间表考虑到了现有疫苗的相关证据,对居住在西班牙的儿童而言堪称最佳。幼儿期的肺炎球菌和水痘免疫接种已纳入地区免疫规划中的所有资助疫苗。此外,该委员会还针对未列入官方日程的疫苗(非资助免疫接种)制定建议,如轮状病毒、B型脑膜炎球菌疫苗和ACWY型脑膜炎球菌疫苗。对于资助免疫接种,推荐采用六价疫苗(DTaP - IPV - Hib - HB)和13价肺炎球菌疫苗的2 + 1策略(2、4、11 - 12个月龄)。建议6岁时用DTaP进行加强免疫,对于已接种2 + 1方案的儿童也建议接种一剂脊髓灰质炎疫苗,青少年和妊娠27至32周的孕妇接种Tdap疫苗。MMR(12个月龄和2 - 4岁)和水痘(15个月龄和2 - 4岁)应采用两剂接种方案。12岁女孩人乳头瘤病毒疫苗两剂接种方案(0、6个月)的覆盖率应予以提高。还应向男性青少年提供关于四价人乳头瘤病毒疫苗潜在益处的信息和建议。ACWY型脑膜炎球菌疫苗是青少年的最佳选择。对于推荐的非资助免疫接种,由于目前西班牙社区药房有货,CAV - AEP建议采用3 + 1方案接种B型脑膜炎球菌疫苗。CAV - AEP要求将该疫苗纳入资助统一时间表。建议所有婴儿接种轮状病毒疫苗。

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