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[西班牙儿科学会免疫接种计划:2018年建议]

[Immunisation schedule of the Spanish Association of Paediatrics: 2018 recommendations].

作者信息

Moreno-Pérez David, Álvarez García Francisco José, Álvarez Aldeán Javier, Cilleruelo Ortega María José, Garcés Sánchez María, García Sánchez Nuria, Hernández Merino Ángel, Méndez Hernández María, Merino Moína Manuel, Montesdeoca Melián Abián, Ruiz-Contreras Jesús

出版信息

An Pediatr (Engl Ed). 2018 Jan;88(1):53.e1-53.e9. doi: 10.1016/j.anpedi.2017.10.001.

DOI:10.1016/j.anpedi.2017.10.001
PMID:29301718
Abstract

The Advisory Committee on Vaccines of the Spanish Association of Paediatrics annually publishes the immunisation schedule considered optimal for children resident in Spain, according to available evidence on current vaccines. Regarding funded immunisations, 2+1 strategy (2, 4, 11-12 months) with hexavalent (DTPa-IPV-Hib-HB) and 13-valent pneumococcal vaccines are recommended. Administration of the 6-year booster dose with DTPa is recommended, and a poliomyelitis dose for children who had received the 2+1 scheme, as well as Tdap vaccine for adolescents and pregnant women in every pregnancy between 27 and 32 weeks' gestation. The two-dose scheme should be used for MMR (12 months and 2-4 years) and varicella (15 months and 2-4 years). MMRV vaccine could be applied as the second dose if available. Coverage of human papillomavirus vaccination in girls aged 12 with a two dose scheme (0, 6 months) should be improved. Information and recommendation for male adolescents about potential beneficial effects of this immunisation should be provided as well. The new 9 genotypes vaccine is now available, expanding the coverage for both gender. Regarding non-funded immunisations, Committee on Vaccines of the Spanish Association of Paediatrics recommends meningococcal B vaccination, with a 3+1 schedule, and requests to be included in the National Immunisation Program. Tetravalent meningococcal vaccine (MenACWY) is recommended to adolescents (14-18 years) who are going to live in countries with systematic vaccination against ACWY serogroups, and people >6 weeks of age with risk factors or travellers to countries with very high incidence. Vaccination against rotavirus is recommended in all infants.

摘要

西班牙儿科学会疫苗咨询委员会每年都会根据现有疫苗的证据,公布一份被认为对居住在西班牙的儿童最为理想的免疫接种计划。关于公费免疫接种,建议采用六价疫苗(白百破-灭活脊髓灰质炎疫苗-流感嗜血杆菌-乙肝疫苗)和13价肺炎球菌疫苗的2+1策略(2、4、11-12个月)。建议在6岁时加强接种白百破疫苗,对已接种2+1方案的儿童接种一剂脊髓灰质炎疫苗,对青少年和妊娠27至32周的孕妇每次妊娠接种破伤风类毒素、白喉、无细胞百日咳疫苗。麻疹、腮腺炎、风疹联合疫苗(MMR)和水痘疫苗应采用两剂接种方案(12个月和2-4岁)。如有条件,第二剂可接种麻疹、腮腺炎、风疹和水痘联合疫苗(MMRV)。应提高12岁女孩人乳头瘤病毒疫苗两剂接种方案(0、6个月)的覆盖率。还应向男性青少年提供有关该疫苗潜在益处的信息和建议。新型9基因型疫苗现已上市,扩大了对两性的覆盖范围。关于自费免疫接种,西班牙儿科学会疫苗委员会建议采用3+1接种方案接种B型脑膜炎球菌疫苗,并要求将其纳入国家免疫计划。对于将前往对A、C、W、Y血清群进行系统性疫苗接种国家生活的青少年(14-18岁),以及6周龄以上有危险因素的人群或前往发病率极高国家的旅行者,建议接种四价脑膜炎球菌疫苗(A、C、W、Y群)。建议所有婴儿接种轮状病毒疫苗。

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