• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

罗哌卡因用于胸腰段交界处急性骨折手术的局部浸润镇痛

Local infiltration analgesia with ropivacaine in acute fracture of thoracolumbar junction surgery.

作者信息

Swennen C, Bredin S, Eap C, Mensa C, Ohl X, Girard V

机构信息

Department of Orthopaedic Surgery, Reims Teaching Hospital, 45, rue Cognacq-Jay, 51092 Reims, France.

Department of Orthopaedic Surgery, Reims Teaching Hospital, 45, rue Cognacq-Jay, 51092 Reims, France.

出版信息

Orthop Traumatol Surg Res. 2017 Apr;103(2):291-294. doi: 10.1016/j.otsr.2016.11.012. Epub 2016 Dec 28.

DOI:10.1016/j.otsr.2016.11.012
PMID:28038991
Abstract

STUDY DESIGN

Retrospective study.

INTRODUCTION

Local infiltration analgesia is effective in many surgeries as knee arthroplasty, but the analgesic efficacy of local infiltration analgesia with ropivacaine in trauma spine surgery in T10 to L2 has not been clarified. We conducted a trial to assess the analgesic efficacy of intraoperative local infiltration analgesia (LIA) with ropivacaine.

OBJECTIVE

The aim of the present study was to clarify the effect of intraoperative local infiltration analgesia with ropivacaine on postoperative pain for patients undergoing thoracolumbar junction fracture surgery.

METHODS

In a retrospective study, in 76 patients undergoing spine surgery for thoracolumbar junction fracture, 20ml of ropivacaine 7.5% (n R group=38) was infiltrated using a systematic technique, or no infiltration was realized (n M group=38). We assessed postoperative pain with Visual Analogue Scale (VAS) and morphine consumption in the 24 first hours.

RESULTS

VAS pain score upon awakening and at 2hours postoperatively were significantly lower in the ropivacaine group (P=0.01 and P=0.002). Rescue opioid requirement during the 24 first hours were about 50% lower in the ropivacaine group (P=0.01). No local or systemic side effects were observed.

CONCLUSION

Intraoperative LIA with ropivacaine in thoracolumbar junction fracture surgery may have an analgesic effect in postoperative pain control (24hours) with a reduction of VAS and morphine consumption.

摘要

研究设计

回顾性研究。

引言

局部浸润镇痛在许多手术如膝关节置换术中是有效的,但罗哌卡因局部浸润镇痛在胸10至腰2创伤性脊柱手术中的镇痛效果尚未明确。我们进行了一项试验以评估术中罗哌卡因局部浸润镇痛(LIA)的镇痛效果。

目的

本研究的目的是阐明术中罗哌卡因局部浸润镇痛对胸腰段骨折手术患者术后疼痛的影响。

方法

在一项回顾性研究中,76例接受胸腰段骨折脊柱手术的患者,38例采用系统技术浸润20ml 7.5%罗哌卡因(R组),38例未进行浸润(M组)。我们用视觉模拟评分法(VAS)和术后24小时内吗啡消耗量评估术后疼痛。

结果

罗哌卡因组术后苏醒时和术后2小时的VAS疼痛评分显著更低(P = 0.01和P = 0.002)。罗哌卡因组术后24小时内的补救性阿片类药物需求量降低约50%(P = 0.01)。未观察到局部或全身副作用。

结论

胸腰段骨折手术中术中使用罗哌卡因进行局部浸润镇痛可能对术后疼痛控制(24小时)有镇痛作用,可降低VAS评分和吗啡消耗量。

相似文献

1
Local infiltration analgesia with ropivacaine in acute fracture of thoracolumbar junction surgery.罗哌卡因用于胸腰段交界处急性骨折手术的局部浸润镇痛
Orthop Traumatol Surg Res. 2017 Apr;103(2):291-294. doi: 10.1016/j.otsr.2016.11.012. Epub 2016 Dec 28.
2
Local infiltration analgesia versus intrathecal morphine for postoperative pain management after total knee arthroplasty: a randomized controlled trial.局部浸润镇痛与鞘内吗啡用于全膝关节置换术后疼痛管理的随机对照试验。
Anesth Analg. 2011 Oct;113(4):926-33. doi: 10.1213/ANE.0b013e3182288deb. Epub 2011 Aug 4.
3
Local infiltration analgesia or femoral nerve block for postoperative pain management in patients undergoing total hip arthroplasty. A randomized, double-blind study.全髋关节置换术患者术后疼痛管理采用局部浸润镇痛或股神经阻滞:一项随机双盲研究。
Scand J Pain. 2017 Jul;16:223-230. doi: 10.1016/j.sjpain.2017.05.002. Epub 2017 Jun 1.
4
Continuous epicapsular ropivacaine 0.3% infusion after minimally invasive hip arthroplasty: a prospective, randomized, double-blinded, placebo-controlled study comparing continuous wound infusion with morphine patient-controlled analgesia.微创髋关节置换术后连续囊外罗哌卡因 0.3%输注:一项前瞻性、随机、双盲、安慰剂对照研究,比较连续伤口输注与吗啡患者自控镇痛。
Anesth Analg. 2012 Feb;114(2):456-61. doi: 10.1213/ANE.0b013e318239dc64. Epub 2011 Nov 10.
5
Postoperative Analgesia After Wound Infiltration With Tramadol and Dexmedetomidine as an Adjuvant to Ropivacaine for Lumbar Discectomies: A Randomized-controlled Clinical Trial.曲马多和右美托咪定辅助罗哌卡因浸润用于腰椎间盘切除术的术后镇痛:一项随机对照临床试验。
J Neurosurg Anesthesiol. 2017 Oct;29(4):433-438. doi: 10.1097/ANA.0000000000000422.
6
Postoperative pain relief after total hip arthroplasty: a randomized, double-blind comparison between intrathecal morphine and local infiltration analgesia.全髋关节置换术后的疼痛缓解:鞘内吗啡与局部浸润镇痛的随机、双盲比较。
Br J Anaesth. 2013 Nov;111(5):793-9. doi: 10.1093/bja/aet248. Epub 2013 Jul 19.
7
Continuous saphenous nerve block as supplement to single-dose local infiltration analgesia for postoperative pain management after total knee arthroplasty.持续隐神经阻滞作为单次局部浸润镇痛在全膝关节置换术后疼痛管理中的补充。
Reg Anesth Pain Med. 2013 Mar-Apr;38(2):106-11. doi: 10.1097/AAP.0b013e31827900a9.
8
Reduced morphine consumption and pain intensity with local infiltration analgesia (LIA) following total knee arthroplasty.全膝关节置换术后局部浸润镇痛(LIA)可减少吗啡用量和疼痛强度。
Acta Orthop. 2010 Jun;81(3):354-60. doi: 10.3109/17453674.2010.487241.
9
Single-shot intraoperative local anaesthetic infiltration does not reduce morphine consumption after total hip arthroplasty: a double-blinded placebo-controlled randomized study.单次术中局部麻醉浸润并不能减少全髋关节置换术后吗啡的用量:一项双盲安慰剂对照随机研究。
Br J Anaesth. 2014 Apr;112(4):722-8. doi: 10.1093/bja/aet439. Epub 2014 Jan 14.
10
A new cocktail formula with diprospan of local infiltration analgesia in primary total hip arthroplasty: A prospective, randomized, controlled, observer-blinded study.局部浸润镇痛复合地塞米松鸡尾酒配方在初次全髋关节置换术中的应用:一项前瞻性、随机、对照、观察者盲法研究。
Orthop Surg. 2022 Aug;14(8):1799-1807. doi: 10.1111/os.13288. Epub 2022 Jul 13.

引用本文的文献

1
Effects of dexmedetomidine-ropivacaine assisted combined spinal-epidural anesthesia on neutrophil-lymphocyte ratio and postoperative delirium in elderly patients with intertrochanteric femoral fracture.右美托咪定-罗哌卡因辅助腰麻-硬膜外联合麻醉对老年股骨转子间骨折患者中性粒细胞与淋巴细胞比值及术后谵妄的影响
Front Pharmacol. 2025 Jan 30;15:1454452. doi: 10.3389/fphar.2024.1454452. eCollection 2024.
2
Wound infiltration with ropivacaine as an adjuvant to patient controlled analgesia for transforaminal lumbar interbody fusion: a retrospective study.罗哌卡因切口浸润作为经椎间孔腰椎体间融合术患者自控镇痛的辅助治疗:一项回顾性研究。
BMC Anesthesiol. 2020 Nov 18;20(1):288. doi: 10.1186/s12871-020-01205-5.