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为什么南亚人似乎能免受心房颤动的影响?对现有证据的综述。

Why are South Asians seemingly protected against the development of atrial fibrillation? A review of current evidence.

机构信息

Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. Electronic address: James.O'

Department of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.

出版信息

Trends Cardiovasc Med. 2017 May;27(4):249-257. doi: 10.1016/j.tcm.2016.11.004. Epub 2016 Nov 25.

DOI:10.1016/j.tcm.2016.11.004
PMID:28040325
Abstract

Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia and is strongly associated with conditions such as valvular heart disease, coronary artery disease and particularly hypertension and diabetes mellitus. The South Asian ethnic group have high rates of these conditions and so would be expected to be at significant risk of AF. However, observational studies have consistently shown that South Asians have a lower prevalence of AF compared with Caucasians. This article summarizes current evidence surrounding the development of AF and its relationship to ethnicity, offers potential reasons for this disparity and identifies future areas of research.

摘要

心房颤动(AF)是最常见的持续性心律失常,与瓣膜性心脏病、冠状动脉疾病,尤其是高血压和糖尿病等疾病密切相关。南亚裔族群这些疾病的发病率较高,因此预计他们患 AF 的风险很大。然而,观察性研究一致表明,南亚裔人群患 AF 的比例低于白种人。本文总结了目前关于 AF 发展及其与种族关系的证据,提出了这种差异的潜在原因,并确定了未来的研究领域。

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