• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Biochemical studies of the iron cores and polypeptide shells of haemosiderin isolated from patients with primary or secondary haemochromatosis.

作者信息

Ward R J, O'Connell M J, Dickson D P, Reid N M, Wade V J, Mann S, Bomford A, Peters T J

机构信息

Department of Clinical Biochemistry, King's College School of Medicine and Dentistry, London, U.K.

出版信息

Biochim Biophys Acta. 1989 Oct 13;993(1):131-3. doi: 10.1016/0304-4165(89)90153-0.

DOI:10.1016/0304-4165(89)90153-0
PMID:2804120
Abstract

Haemosiderin isolated from different iron-loading syndromes, primary haemochromatosis (PHC) and secondary haemochromatosis (SHC) biochemically exhibited differences in both their iron core and peptide composition. The rate of release of iron from PHC haemosiderin to oxalate was 3-fold greater than that from SHC haemosiderin. The major peptides separated by SDS-PAGE showed a major band at Mr 20,000 for PHC haemosiderin and at Mr 15,000 for SHC haemosiderin.

摘要

相似文献

1
Biochemical studies of the iron cores and polypeptide shells of haemosiderin isolated from patients with primary or secondary haemochromatosis.
Biochim Biophys Acta. 1989 Oct 13;993(1):131-3. doi: 10.1016/0304-4165(89)90153-0.
2
Structural specificity of haemosiderin iron cores in iron-overload diseases.铁过载疾病中含铁血黄素铁芯的结构特异性
FEBS Lett. 1988 Jul 4;234(1):69-72. doi: 10.1016/0014-5793(88)81305-x.
3
Iron K-edge absorption spectroscopic investigations of the cores of ferritin and haemosiderins.铁蛋白和血铁黄素核心的铁K边吸收光谱研究。
Biochim Biophys Acta. 1991 Dec 6;1115(2):145-50. doi: 10.1016/0304-4165(91)90023-a.
4
Biochemical studies on the isolation and characterization of human spleen haemosiderin.关于人脾脏含铁血黄素的分离与特性的生化研究。
Biochem J. 1984 Oct 1;223(1):31-8. doi: 10.1042/bj2230031.
5
Further characterisation of forms of haemosiderin in iron-overloaded tissues.铁过载组织中含铁血黄素形式的进一步表征。
Eur J Biochem. 1994 Oct 1;225(1):187-94. doi: 10.1111/j.1432-1033.1994.00187.x.
6
Haemosiderin and tissue damage.
Cell Biochem Funct. 1984 Oct;2(4):186-94. doi: 10.1002/cbf.290020402.
7
Studies on haemosiderin and ferritin from iron-loaded rat liver.铁负荷大鼠肝脏中铁蛋白和含铁血黄素的研究。
Biol Met. 1988;1(1):33-42. doi: 10.1007/BF01128015.
8
Does the haemosiderin iron core determine its potential for chelation and the development of iron-induced tissue damage?含铁血黄素的铁芯是否决定了其螯合潜力以及铁诱导的组织损伤的发展？
J Inorg Biochem. 2000 Apr;79(1-4):311-7. doi: 10.1016/s0162-0134(99)00237-8.
9
Distribution of liver haemosiderin iron in 187 patients with various types of hepatic diseases.187例不同类型肝病患者肝脏含铁血黄素铁的分布情况。
APMIS. 1996 Mar;104(3):220-6. doi: 10.1111/j.1699-0463.1996.tb00711.x.
10
Iron and isoferritins in iron overload.铁过载中的铁与异铁蛋白
Clin Sci (Lond). 1982 May;62(5):529-40. doi: 10.1042/cs0620529.

引用本文的文献

1
Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions.慢性多发性硬化症病变中铁和锌的不同模式的致病意义。
Acta Neuropathol. 2017 Jul;134(1):45-64. doi: 10.1007/s00401-017-1696-8. Epub 2017 Mar 22.
2
Ferritins: furnishing proteins with iron.铁蛋白：为蛋白质提供铁。
J Biol Inorg Chem. 2016 Mar;21(1):13-28. doi: 10.1007/s00775-016-1336-0. Epub 2016 Jan 29.
3
Hepatic iron deposition in human disease and animal models.人类疾病和动物模型中的肝脏铁沉积。
Biometals. 1996 Apr;9(2):205-9. doi: 10.1007/BF00144626.