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[甲状腺激素预防应激期间心脏收缩功能障碍]

[Thyroid hormone prevention of disorders of cardiac contractile function during stress].

作者信息

Bozhko A P, Sukhorukova T A

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1989(6):50-3.

PMID:2804173
Abstract

The depression of cardiac contractility has been observed in rats during the immobilized stress in state of relative physiological rest and maximal load. In the animals pretreated with thyroid after stress the indexes of intensity and rate of myocardial contraction and relaxation didn't differ from the control, and during the maximal load the myocardium was characterized by the less expressed decrease of the structure functioning intensity and the higher rate of relaxation. The data obtained show that the physiological doses of thyroid hormones prevent the myocardium from contractile disorders during stress.

摘要

在相对生理静息和最大负荷状态下的固定应激期间,已观察到大鼠心脏收缩力下降。在应激后用甲状腺素预处理的动物中,心肌收缩和舒张的强度及速率指标与对照组无差异,且在最大负荷时,心肌的特点是结构功能强度下降程度较轻且舒张速率较高。所获数据表明,生理剂量的甲状腺激素可防止应激期间心肌出现收缩紊乱。

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