Balamurugan Namasivayam, Arathisenthil S V, Senthilkumaran Subramanian, Thirumalaikolundusubramanian Ponniah
Department of Neurosciences, SIMS Chellum hospital, Salem, Tamil Nadu, India.
Department of oral Pathology, Be Well hospital, Erode, Tamil Nadu, India.
Am J Emerg Med. 2017 May;35(5):805.e1-805.e2. doi: 10.1016/j.ajem.2016.11.055. Epub 2016 Dec 1.
Numb chin syndrome (NCS) is a rare yet potentially ominous sensory neuropathy in the distribution of the mental or inferior alveolar nerve characterized by unilateral hypoesthesia over the lower lip, chin and occasionally gingival mucosa. Recognizing NCS is clinically important as this may be a subtle sign of occult malignancy progression or heralding the relapses. It may also occur in benign disease, both systemic and dental in origin. Current expert opinion is that patients with NCS without apparent cause should be assumed to have a malignant etiology until proven otherwise Lossos and Siegal (1992) [1]. Here we report a relapse of Non-Hodgkin lymphoma with NCS with no evidence of metastasis.
麻木性颏部综合征（NCS）是一种罕见但可能预后不良的感觉神经病变，累及颏神经或下牙槽神经分布区域，其特征为下唇、颏部，偶尔还有牙龈黏膜单侧感觉减退。认识到NCS在临床上很重要，因为这可能是隐匿性恶性肿瘤进展的微妙迹象或预示着复发。它也可能发生在良性疾病中，病因既有全身性的，也有牙科源性的。目前的专家意见是，在未证实有其他病因之前，应假定无明显病因的NCS患者存在恶性病因（洛索斯和西格尔，1992年[1]）。在此，我们报告一例非霍奇金淋巴瘤伴NCS复发且无转移证据的病例。
