喹啉：微波辅助合成及其抗真菌、抗癌和自由基清除特性。
Quinolines: Microwave-assisted synthesis and their antifungal, anticancer and radical scavenger properties.
作者信息
Liberto Natália Aparecida, Simões Juliana Baptista, de Paiva Silva Sarah, da Silva Cristiane Jovelina, Modolo Luzia Valentina, de Fátima Ângelo, Silva Luciana Maria, Derita Marcos, Zacchino Susana, Zuñiga Omar Miguel Portilla, Romanelli Gustavo Pablo, Fernandes Sergio Antonio
机构信息
Grupo de Química Supramolecular e Biomimética (GQSB), Departamento de Química, Universidade Federal de Viçosa, Viçosa, MG 36570-900, Brazil.
Grupo de Estudos em Bioquímica de Plantas (GEBioPlan), Departamento de Botânica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, Brazil.
出版信息
Bioorg Med Chem. 2017 Feb 1;25(3):1153-1162. doi: 10.1016/j.bmc.2016.12.023. Epub 2016 Dec 21.
An efficient method for the synthesis of quinolines using microwave irradiation was developed providing 28 quinolines with good yields. The reaction procedures are environmentally friendly, convenient, mild and of easy work-up. Quinolines were evaluated for their antifungal, anticancer and antioxidant properties and exhibited high activities in all tests performed.
开发了一种利用微波辐射合成喹啉的有效方法，得到了28种喹啉，产率良好。该反应过程环境友好、方便、温和且后处理容易。对喹啉的抗真菌、抗癌和抗氧化性能进行了评估，在所有进行的测试中均表现出高活性。
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