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高龄对机器人辅助肺叶切除术后围手术期结局的影响:287 例连续病例的回顾性分析。

Effect of advanced age on peri-operative outcomes after robotic-assisted pulmonary lobectomy: Retrospective analysis of 287 consecutive cases.

机构信息

Morsani College of Medicine, University of South Florida Health, Tampa, FL USA.

Department of Surgery, University of South Florida, Health Morsani College of Medicine, Tampa, FL USA.

出版信息

J Geriatr Oncol. 2017 Mar;8(2):102-107. doi: 10.1016/j.jgo.2016.11.003. Epub 2016 Dec 29.

Abstract

OBJECTIVES

We investigated whether advanced age affects peri-operative outcomes after robotic-assisted pulmonary lobectomies.

MATERIALS AND METHODS

We retrospectively analyzed patients who underwent robotic-assisted lobectomy by one surgeon over a 5-year period. Rates of postoperative complications were compared according to age group. Other outcomes, such as intraoperative complications, hospital length of stay (LOS), and in-hospital mortality, were also compared.

RESULTS

A total of 287 patients were included (mean age 67.1yr). Group A had 65 patients of advanced age≥75yr (range 75-87yr; 37 men, 28 women); Group B had 222 patients aged <75yr (range 29-74yr; 95 men, 127 women). Group A had 10/65 (15.4%) patients with robotic-related intraoperative complications, compared to 10/222 (4.5%) for Group B (p=0.002), with the most frequent intraoperative complications being bleeding from a pulmonary vessel (10.8% vs. 4.5%, p=0.06), bronchial injury (3.1% vs. 0.9%, p=0.18), and injury to the phrenic or recurrent laryngeal nerve (1.5% vs. 0.4%, p=0.33). There were 28/65 (43.1%) patients in Group A with postoperative complications compared to 76/222 (34.2%) in Group B (p=0.19). While operative times were similar (p=0.42), Group A had longer median hospital LOS of 6±0.9days compared to 4±0.3days for Group B (p=0.02).

CONCLUSION

While younger patients have lower risk of robotic-related intraoperative complications and shorter hospital LOS, elderly patients do not have increased overall or emergent conversion rates to open lobectomy, overall postoperative complications rates, or in-house mortality compared to younger patients. Thus, robotic-assisted pulmonary lobectomy is feasible and relatively safe for patients of advanced age.

摘要

目的

我们研究了高龄是否会影响机器人辅助肺叶切除术后的围手术期结果。

材料和方法

我们回顾性分析了一位外科医生在 5 年内进行机器人辅助肺叶切除术的患者。根据年龄组比较术后并发症发生率。还比较了其他结果,如术中并发症、住院时间(LOS)和院内死亡率。

结果

共纳入 287 例患者(平均年龄 67.1 岁)。A 组 65 例为高龄≥75 岁(75-87 岁;37 名男性,28 名女性);B 组 222 例年龄<75 岁(29-74 岁;95 名男性,127 名女性)。A 组有 10/65(15.4%)例患者发生机器人相关术中并发症,而 B 组为 10/222(4.5%)(p=0.002),最常见的术中并发症为肺血管出血(10.8%比 4.5%,p=0.06)、支气管损伤(3.1%比 0.9%,p=0.18)和膈神经或喉返神经损伤(1.5%比 0.4%,p=0.33)。A 组 28/65(43.1%)例患者术后发生并发症,而 B 组 76/222(34.2%)例患者术后发生并发症(p=0.19)。手术时间相似(p=0.42),A 组中位住院时间为 6±0.9 天,而 B 组为 4±0.3 天(p=0.02)。

结论

与年轻患者相比,高龄患者机器人相关术中并发症和住院时间较长,但与年轻患者相比,高龄患者的总体或急诊转为开胸肺叶切除术、总体术后并发症发生率或院内死亡率并未增加。因此,机器人辅助肺叶切除术对于高龄患者是可行且相对安全的。

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