Moran Carthage P, Neary Barra, Doherty Glen A
Carthage P Moran, Barra Neary, Glen A Doherty, Centre for Colorectal Disease, St. Vincent's University Hospital and School of Medicine, University College Dublin, D04 T6F4 Dublin, Ireland.
World J Gastrointest Endosc. 2016 Dec 16;8(20):723-732. doi: 10.4253/wjge.v8.i20.723.
Endoscopy is a keystone in the management of patients with inflammatory bowel disease (IBD). It is the fundamental diagnostic tool for IBD, and can help discern between ulcerative colitis and Crohn's disease. Endoscopic assessment provides an objective end point in clinical trials, and identifies patients in clinical practice who may benefit from treatment escalation and may assist risk stratification in patients seeking to discontinue therapy. Recent advances in endoscopic assessment of patients with IBD include video capsule endoscopy, and chromoendoscopy. Technological advances enable improved visualization and focused biopsy sampling. Endoscopic resection and close surveillance of dysplastic lesions where feasible is recommended instead of prophylactic colectomy.
内镜检查是炎症性肠病(IBD)患者管理的关键环节。它是IBD的基本诊断工具,有助于区分溃疡性结肠炎和克罗恩病。内镜评估为临床试验提供了客观的终点,并在临床实践中识别出可能从强化治疗中获益的患者,还可协助对寻求停止治疗的患者进行风险分层。IBD患者内镜评估的最新进展包括视频胶囊内镜和色素内镜检查。技术进步使可视化效果改善和活检采样更具针对性。建议在可行的情况下对发育异常病变进行内镜切除并密切监测,而非进行预防性结肠切除术。