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内镜评估在炎症性肠病诊断与管理中的应用

Endoscopic evaluation in diagnosis and management of inflammatory bowel disease.

作者信息

Moran Carthage P, Neary Barra, Doherty Glen A

机构信息

Carthage P Moran, Barra Neary, Glen A Doherty, Centre for Colorectal Disease, St. Vincent's University Hospital and School of Medicine, University College Dublin, D04 T6F4 Dublin, Ireland.

出版信息

World J Gastrointest Endosc. 2016 Dec 16;8(20):723-732. doi: 10.4253/wjge.v8.i20.723.

DOI:10.4253/wjge.v8.i20.723
PMID:28042386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5159670/
Abstract

Endoscopy is a keystone in the management of patients with inflammatory bowel disease (IBD). It is the fundamental diagnostic tool for IBD, and can help discern between ulcerative colitis and Crohn's disease. Endoscopic assessment provides an objective end point in clinical trials, and identifies patients in clinical practice who may benefit from treatment escalation and may assist risk stratification in patients seeking to discontinue therapy. Recent advances in endoscopic assessment of patients with IBD include video capsule endoscopy, and chromoendoscopy. Technological advances enable improved visualization and focused biopsy sampling. Endoscopic resection and close surveillance of dysplastic lesions where feasible is recommended instead of prophylactic colectomy.

摘要

内镜检查是炎症性肠病(IBD)患者管理的关键环节。它是IBD的基本诊断工具,有助于区分溃疡性结肠炎和克罗恩病。内镜评估为临床试验提供了客观的终点,并在临床实践中识别出可能从强化治疗中获益的患者,还可协助对寻求停止治疗的患者进行风险分层。IBD患者内镜评估的最新进展包括视频胶囊内镜和色素内镜检查。技术进步使可视化效果改善和活检采样更具针对性。建议在可行的情况下对发育异常病变进行内镜切除并密切监测,而非进行预防性结肠切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcac/5159670/0df0ccba3968/WJGE-8-723-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcac/5159670/0df0ccba3968/WJGE-8-723-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcac/5159670/0df0ccba3968/WJGE-8-723-g001.jpg

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Increased risk of colorectal neoplasia in patients with primary sclerosing cholangitis and inflammatory bowel disease: a meta-analysis of 16 observational studies.
炎症性肠病患者临床症状及实验室检查结果与内镜严重程度指数的相关性
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Comparison of small-bowel colon capsule endoscopy system to conventional colonoscopy for the evaluation of ulcerative colitis activity.小肠结肠胶囊内镜系统与传统结肠镜检查在评估溃疡性结肠炎活动度方面的比较。
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