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炎症性肠病患者的结直肠癌筛查。我们是否应该对所有患者都进行色素内镜检查?

Screening for colorectal cancer in patients with inflammatory bowel disease. Should we already perform chromoendoscopy in all our patients?

作者信息

Huguet Jose María, Suárez Patrícia, Ferrer-Barceló Luis, Iranzo Isabel, Sempere Javier

机构信息

Digestive Disease Department, Hospital General Universitario de Valencia, Valencia 46014, Valencia, Spain.

出版信息

World J Gastrointest Endosc. 2018 Nov 16;10(11):322-325. doi: 10.4253/wjge.v10.i11.322.

Abstract

Patients with inflammatory bowel disease (commonly known as IBD) have a greater risk of colorectal cancer than the general population. Therefore, they are included in special programs for screening and follow-up. Chromoendoscopy, which has a high diagnostic yield in the detection of neoplasia, is generally the recommended endoscopy technique. However, this procedure does have some disadvantages (long examination time, need for optimal bowel preparation, specialist training), which increase its cost. How then can we overcome these barriers? First, it is necessary to educate hospital managers and directors of the advantages of chromoendoscopy in patients with IBD. Second, at least one endoscopist per center should be a specialist in the technique. Third, we should train nursing staff in the preparation of the dye. Finally, each examination should be given the time it needs. Even though clinical practice guidelines do not yet recommend the use of virtual imaging techniques such as narrow band imaging, a recent study reported no differences between the two approaches for the detection of tumors. Therefore, we believe that all patients should undergo chromoendoscopy. In the future, centers without access to dyes or where other barriers exist should at least perform narrow band imaging.

摘要

炎症性肠病(通常称为IBD)患者患结直肠癌的风险高于普通人群。因此,他们被纳入特殊的筛查和随访项目。染色内镜检查在肿瘤检测中具有较高的诊断率,通常是推荐的内镜检查技术。然而,该检查确实存在一些缺点(检查时间长、需要最佳的肠道准备、专业培训),这增加了其成本。那么我们如何克服这些障碍呢?首先,有必要向医院管理人员和主任宣传染色内镜检查对IBD患者的优势。其次,每个中心至少应有一名内镜医师是该技术的专家。第三,我们应该培训护理人员进行染料准备。最后,每次检查都应给予所需的时间。尽管临床实践指南尚未推荐使用窄带成像等虚拟成像技术,但最近一项研究报告称,两种检测肿瘤的方法之间没有差异。因此,我们认为所有患者都应接受染色内镜检查。未来,无法获得染料或存在其他障碍的中心至少应进行窄带成像。

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