Seredenin S B, Badyshtov B A, Egorov D Iu
Biull Eksp Biol Med. 1989 Jul;108(7):46-8.
C57BL/6 and BALB/c mice differing in their response to emotional-stress stimulus in the open field test as well as their F1-hybrids (C57BL/6XBALB/c) with the response similar to that of the C57BL/6 strain have been examined for the initial level and changes in the total content of lipids as well as of TBA-active products and diene conjugates in the brain and liver. The strains have been demonstrated to differ in the initial content of lipids and lipid peroxidation products, but C57BL/6 mice and F1-hybrids showed similar dynamics of changes. It is concluded that different strains are characterized by specific dynamics of lipid peroxidation products. The relevance of the results obtained to the mechanism of some unfavourable consequences of emotional-stress reactions is discussed.
在旷场试验中对情绪应激刺激反应不同的C57BL/6和BALB/c小鼠，以及反应与C57BL/6品系相似的它们的F1杂种（C57BL/6XBALB/c），已就大脑和肝脏中脂质的初始水平以及脂质总量、TBA活性产物和二烯共轭物的变化进行了检测。已证明这些品系在脂质和脂质过氧化产物的初始含量上存在差异，但C57BL/6小鼠和F1杂种显示出相似的变化动态。得出的结论是，不同品系具有脂质过氧化产物的特定动态特征。讨论了所得结果与情绪应激反应某些不良后果机制的相关性。
