Rahimian Shayan, Daş Gürbüz, Gauly Matthias
University of Göttingen, Department of Animal Sciences, Albrecht-Thaer-Weg 3, 37075, Göttingen, Germany.
Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology, Wilhelm-Stahl-Allee 2 18196, Dummerstorf, Germany.
Vet Parasitol. 2017 Jan 15;233:43-47. doi: 10.1016/j.vetpar.2016.11.014. Epub 2016 Nov 19.
Maternally derived antibodies can provide partial protection against certain bacterial and viral infections. We investigated whether chicks descending from nematode-infected hens are more resistant against Ascaridia galli, a prevalent gastrointestinal nematode, than chicks from nematode-free mothers. One-day-old chicks (N=153) from infected (mab+; maternal antibody+) or uninfected control dams (mab-) were experimentally infected with A. galli at two different levels (100 or 1000 eggs/chick). The worm burdens of the chicks were determined at 6 weeks post infection. There was a high correlation (r=0.89) between A. galli-specific antibody concentrations in dam plasma and egg yolk. There was no difference between worm burdens of chicks descending from infected or uninfected dams (P=0.892), indicating no maternally derived protection against A. galli. Chicks receiving the higher infection dose had higher worm burdens (P<0.05). Although there was no difference (P>0.05) between worm counts of female and male chicks infected with 100 eggs, females chicks infected with 100 eggs harboured longer and heavier female worms. We conclude that there is no protective maternal immunity against A. galli infection.
母源抗体可为抵抗某些细菌和病毒感染提供部分保护。我们研究了来自感染线虫母鸡的雏鸡是否比来自未感染线虫母鸡的雏鸡对鸡蛔虫（一种常见的胃肠道线虫）更具抵抗力。将来自感染（mab +；母源抗体阳性）或未感染对照母禽（mab -）的1日龄雏鸡（N = 153）以两种不同水平（100或1000个卵/雏鸡）进行鸡蛔虫实验感染。在感染后6周测定雏鸡的虫负荷。母禽血浆和蛋黄中鸡蛔虫特异性抗体浓度之间存在高度相关性（r = 0.89）。来自感染或未感染母禽的雏鸡的虫负荷没有差异（P = 0.892），表明不存在母源抗鸡蛔虫保护作用。接受较高感染剂量的雏鸡有更高的虫负荷（P <0.05）。虽然感染100个卵的雌性和雄性雏鸡的虫数没有差异（P> 0.05），但感染100个卵的雌性雏鸡体内的雌虫更长、更重。我们得出结论，不存在针对鸡蛔虫感染的母源保护性免疫。
