Tchoukoua Abdou, Tabopda Turibio Kuiate, Uesugi Shota, Ohno Misa, Kimura Ken-Ichi, Kwon Eunsang, Momma Hiroyuki, Horo Ibrahim, Çalişkan Özgen Alankuş, Shiono Yoshihito, Ngadjui Bonaventure Tchaleu
Department of Organic Chemistry, University of Yaounde 1, P.O. Box 812, Yaounde, Cameroon; Faculty of Agriculture, Yamagata University, 1-23, Wakaba-machi, Tsuruoka, Yamagata, 997-8555, Japan.
Department of Organic Chemistry, University of Yaounde 1, P.O. Box 812, Yaounde, Cameroon.
Phytochemistry. 2017 Apr;136:31-38. doi: 10.1016/j.phytochem.2016.12.019. Epub 2016 Dec 30.
Seven previously undescribed bidesmosidic triterpenoid saponins named albidosides A - G, were isolated from a methanol extract of the roots of Acacia albida. Their structures were elucidated using 1D and 2D NMR spectroscopy and mass spectrometry and determined to be bidesmosides of oleanolic acid and of 16α-hydroxyoleanolic acid. Albidosides B - G were assayed for their cytotoxicity against HeLa and HL60 cells using MTT method and microscopic observation.
从微白相思树根的甲醇提取物中分离出7种以前未描述过的双糖苷三萜皂苷，命名为白苷A - G。通过一维和二维核磁共振光谱以及质谱对其结构进行了阐明，并确定它们是齐墩果酸和16α-羟基齐墩果酸的双糖苷。使用MTT法和显微镜观察对白苷B - G对HeLa和HL60细胞的细胞毒性进行了测定。
