对男男性行为年轻黑人中抗逆转录病毒药物依从性的纵向分析。
A Longitudinal Analysis of Antiretroviral Adherence Among Young Black Men Who Have Sex With Men.
作者信息
Voisin Dexter R, Quinn Katherine, Kim Dong Ha, Schneider John
机构信息
School of Social Service Administration, University of Chicago, Chicago, Illinois; STI/HIV Intervention Network, University of Chicago, Chicago, Illinois; Third Coast Center for AIDS Research, University of Chicago and Northwestern University, Chicago, Illinois; Chicago Center for HIV Elimination, University of Chicago, Chicago, Illinois.
Center for AIDS Intervention Research, Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
出版信息
J Adolesc Health. 2017 Apr;60(4):411-416. doi: 10.1016/j.jadohealth.2016.10.428. Epub 2016 Dec 30.
PURPOSE
Young black men who have sex with men (YBMSM) experience poorer antiretroviral therapy (ART) medication adherence relative to their white counterparts. However, few studies have longitudinally examined factors that may correlate with various classifications of ART adherence among this population, which was the primary aim of this study.
METHODS
Project nGage was a randomized controlled trial conducted across five Chicago clinics from 2012 to 2015. Survey and medical records data were collected at baseline and 3- and 12-month periods to assess whether psychological distress, HIV stigma, substance use, family acceptance, social support, and self-efficacy predicted ART medication adherence among 92 YBMSM ages 16-29 years.
RESULTS
Major results controlling for the potential effects of age, education level, employment, and intervention condition indicated that participants with high versus low medication adherence were less likely to report daily/weekly alcohol or marijuana use, had higher family acceptance, and exhibited greater self-efficacy.
CONCLUSIONS
These findings identity important factors that can be targeted in clinical and program interventions to help improve ART medication adherence for YBMSM.
目的
与白人男男性行为者相比，年轻黑人男男性行为者（YBMSM）的抗逆转录病毒疗法（ART）药物依从性较差。然而，很少有研究纵向考察该人群中可能与ART依从性的各种分类相关的因素，这是本研究的主要目的。
方法
“nGage计划”是一项于2012年至2015年在芝加哥五家诊所开展的随机对照试验。在基线以及3个月和12个月时收集调查和医疗记录数据，以评估心理困扰、HIV污名、物质使用、家庭接纳、社会支持和自我效能是否能预测92名年龄在16至29岁的YBMSM的ART药物依从性。
结果
在控制了年龄、教育水平、就业和干预条件的潜在影响后，主要结果表明，药物依从性高与低的参与者相比，前者每日/每周饮酒或使用大麻的可能性较小，家庭接纳度较高，且自我效能更强。
结论
这些发现确定了在临床和项目干预中可以针对的重要因素，以帮助提高YBMSM的ART药物依从性。
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