Mertes H, Defourny L, Tré-Hardy M, Lhommel R, El Khoury G, Rodriguez-Villalobos H, Belkhir L
Cliniques Universitaires St. Luc, Internal Medicine and Infectious Diseases Department, Avenue Hippocrate 10, 1200 Brussels, Belgium.
Cliniques Universitaires St. Luc, Clinical Microbiology Department, Avenue Hippocrate 10, 1200 Brussels, Belgium.
Anaerobe. 2017 Apr;44:23-26. doi: 10.1016/j.anaerobe.2016.12.014. Epub 2016 Dec 30.
Mycotic aortic aneurysm is a rare and challenging complication of aortic homografts caused by an infection and is associated with high morbidity and mortality. We report the first case of an aortic cross homograft mycotic pseudoaneurysm caused by Robinsoniella peoriensis in a 70-year-old man. Our patient underwent surgery for a recurrence of aortic cross mycotic pseudoaneurysm at the level of the aortic homograft he had had 7 years before. A clot-removal of the pseudoaneurysm was surgically carried out and the homograft was completely removed. Anaerobic culture from tissue samples yielded pure growth of a spore-forming Gram-positive rod, identified later as Robinsoniella peoriensis by 16S rRNA gene sequencing. The patient was then discharged with oral clindamycin according to the in vitro susceptibility testing. Identification of R. peoriensis might be challenging in clinical laboratories with no access to molecular methods.
真菌性主动脉瘤是由感染引起的主动脉同种异体移植罕见且具有挑战性的并发症,与高发病率和死亡率相关。我们报告了首例由佩奥里氏罗氏菌引起的主动脉交叉同种异体移植真菌性假性动脉瘤,患者为一名70岁男性。我们的患者因7年前接受过主动脉同种异体移植部位的主动脉交叉真菌性假性动脉瘤复发而接受手术。通过手术清除了假性动脉瘤内的血栓,并完全移除了同种异体移植组织。组织样本的厌氧培养产生了一种形成孢子的革兰氏阳性杆菌的纯培养物,后来通过16S rRNA基因测序鉴定为佩奥里氏罗氏菌。然后根据体外药敏试验,患者口服克林霉素出院。在无法使用分子方法的临床实验室中,鉴定佩奥里氏罗氏菌可能具有挑战性。