Graduate School of Analytical Science and Technology, Chungnam National University , Daejeon 305-764, Republic of Korea.
ACS Appl Mater Interfaces. 2017 Jan 25;9(3):3192-3200. doi: 10.1021/acsami.6b16634. Epub 2017 Jan 12.
An antibacterial continuous flow microreactor was successfully prepared by sequential mussel-inspired surface engineering of microchannels by using catechol-grafted poly(N-vinylpyrrolidone) and immobilization of near-infrared active CsWO nanoparticles inside the polydimethylsiloxane(PDMS)-based microreactors. Excellent phothothermal antibacterial acitivity over 99.9% was accomplished toward Gram-positive and -negative bacteria upon near-infrared irradiation during continuous operation up to 30 days. This was achieved without releasing CsWO nanoparticles from the surface of the microchannels, confirming the robust immobilization of photothermal agents through the mussel-inspired chemistry. The cleaning of used microreactors was easily attainable by simple acid treatment to release immobilized photothermal agents from the surface of the microchannels, enabling efficient recycling of used microreactors.
通过顺序贻贝启发式表面工程，成功制备了一种具有抗菌性能的连续流微反应器，方法是在微通道内接枝儿茶酚的聚（N-乙烯基吡咯烷酮）和固定化近红外活性 CsWO 纳米粒子。在连续运行 30 天的近红外辐射下，对革兰氏阳性菌和革兰氏阴性菌表现出优异的光热抗菌活性，超过 99.9%。这是在 CsWO 纳米粒子不从微通道表面释放的情况下实现的，这证实了通过贻贝启发式化学对光热剂进行了牢固的固定。通过简单的酸处理可以轻松清洗用过的微反应器，从微通道表面释放固定化的光热剂，从而实现用过的微反应器的有效回收。
