Caruso S, Bernardi S, Pasini M, Giuca M R, Docimo R, Continenza M A, Gatto R
Department of Health, Life and Environmental Sciences, University of L'Aquila.
Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa.
Eur J Paediatr Dent. 2016 Dec;17(4):322-326.
Tooth development and mineralisation are processes that derive from different tissues interactions, in particular ectodermal and mesenchymal layers. These interactions are responsible for the formation of unique structures with a particular chemical composition. Despite differences, mineralised tissues are similar and they derive by highly concerted extracellular processes that involve matrix proteins, proteases, and mineral ion fluxes that collectively regulate the nucleation, growth and organisation of forming mineral crystals. This review aims at explaining mineralisation, its stages and when damage occurs and alters the hard tissues structure.
牙齿发育和矿化是源自不同组织相互作用的过程，尤其是外胚层和间充质层之间的相互作用。这些相互作用负责形成具有特定化学成分的独特结构。尽管存在差异，但矿化组织具有相似性，它们通过高度协调的细胞外过程形成，这些过程涉及基质蛋白、蛋白酶和矿质离子通量，共同调节形成中的矿物晶体的成核、生长和组织。本综述旨在解释矿化、其阶段以及损伤发生并改变硬组织结构的时间。
