Leung Tsz Wing, Li Roger Wing-Hong, Kee Chea-Su
School of Optometry, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR.
School of Optometry, University of California, Berkeley, California, United States of America.
PLoS One. 2017 Jan 3;12(1):e0169114. doi: 10.1371/journal.pone.0169114. eCollection 2017.
To evaluate the optical performance of blue-light filtering spectacle lenses and investigate whether a reduction in blue light transmission affects visual performance and sleep quality.
Experiment 1: The relative changes in phototoxicity, scotopic sensitivity, and melatonin suppression of five blue-light filtering plano spectacle lenses were calculated based on their spectral transmittances measured by a spectrophotometer. Experiment 2: A pseudo-randomized controlled study was conducted to evaluate the clinical performance of two blue-light filtering spectacle lenses (BF: blue-filtering anti-reflection coating; BT: brown-tinted) with a regular clear lens (AR) serving as a control. A total of eighty computer users were recruited from two age cohorts (young adults: 18-30 yrs, middle-aged adults: 40-55 yrs). Contrast sensitivity under standard and glare conditions, and colour discrimination were measured using standard clinical tests. After one month of lens wear, subjective ratings of lens performance were collected by questionnaire.
All tested blue-light filtering spectacle lenses theoretically reduced the calculated phototoxicity by 10.6% to 23.6%. Although use of the blue-light filters also decreased scotopic sensitivity by 2.4% to 9.6%, and melatonin suppression by 5.8% to 15.0%, over 70% of the participants could not detect these optical changes. Our clinical tests revealed no significant decrease in contrast sensitivity either with (95% confidence intervals [CI]: AR-BT [-0.05, 0.05]; AR-BF [-0.05, 0.06]; BT-BF [-0.06, 0.06]) or without glare (95% CI: AR-BT [-0.01, 0.03]; AR-BF [-0.01, 0.03]; BT-BF [-0.02, 0.02]) and colour discrimination (95% CI: AR-BT [-9.07, 1.02]; AR-BF [-7.06, 4.46]; BT-BF [-3.12, 8.57]).
Blue-light filtering spectacle lenses can partially filter high-energy short-wavelength light without substantially degrading visual performance and sleep quality. These lenses may serve as a supplementary option for protecting the retina from potential blue-light hazard.
ClinicalTrials.gov NCT02821403.
评估蓝光过滤眼镜片的光学性能,并研究蓝光透过率的降低是否会影响视觉性能和睡眠质量。
实验1:根据用分光光度计测量的五种蓝光过滤平光眼镜片的光谱透过率,计算光毒性、暗视敏感度和褪黑素抑制的相对变化。实验2:进行一项伪随机对照研究,以评估两种蓝光过滤眼镜片(BF:蓝光过滤抗反射涂层;BT:棕色镜片)的临床性能,以普通透明镜片(AR)作为对照。从两个年龄组(年轻人:18 - 30岁,中年人:40 - 55岁)招募了80名计算机用户。使用标准临床测试测量标准条件和眩光条件下的对比敏感度以及颜色辨别能力。佩戴镜片一个月后,通过问卷调查收集对镜片性能的主观评价。
所有测试的蓝光过滤眼镜片理论上可将计算出的光毒性降低10.6%至23.6%。虽然使用蓝光滤镜也会使暗视敏感度降低2.4%至9.6%,褪黑素抑制降低5.8%至15.0%,但超过70%的参与者无法察觉这些光学变化。我们的临床测试显示,在有眩光(95%置信区间[CI]:AR - BT[-0.05, 0.05];AR - BF[-0.05, 0.06];BT - BF[-0.06, 0.06])或无眩光(95%CI:AR - BT[-0.01, 0.03];AR - BF[-0.01, 0.03];BT - BF[-0.02, 0.02])的情况下,对比敏感度均无显著下降,颜色辨别能力也无显著下降(95%CI:AR - BT[-9.07, 1.02];AR - BF[-7.06, 4.46];BT - BF[-3.12, 8.57])。
蓝光过滤眼镜片可部分过滤高能短波光线,而不会显著降低视觉性能和睡眠质量。这些镜片可作为保护视网膜免受潜在蓝光危害的补充选择。
ClinicalTrials.gov NCT02821403。