Lian Yan, Lu Weiwei, Huang Haixiao, Wu Ge, Xu Aiqin, Jin Wanqing
State Key Laboratory of Ophthalmology, Optometry and Vision Science, School of Ophthalmology and Optometry, Affiliated Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Front Neurosci. 2022 Jul 15;16:898489. doi: 10.3389/fnins.2022.898489. eCollection 2022.
To evaluate the long-term effect of two different degrees of blue-light blocking (BB) spectacle lenses on adults' contrast perception under various lighting conditions.
In total, 144 healthy adults aged 24.70 (±4.32 years) were recruited to this randomized controlled trial. The participants were randomly divided into three groups and used three different spectacle lenses (15% BB: 15% blue-blocking spectacle lenses; 30% BB: 30% blue-blocking spectacle lenses; RC: regular clear lenses serving as control). Contrast sensitivity under four light conditions (scotopic and photopic, both with/without glare) was measured using standard clinical tests at baseline, 1 month, 3 months and 6 months of use. The area under the log contrast sensitivity function (AULCSF) was also computed as an index for their overall contrast sensitivity across spatial frequencies.
There was no significant difference in AULCSFs among the three types of spectacle lenses under any light condition (all > 0.81). No statistical difference was found in the AULSCF among the four time points (all > 0.39), with no interaction between the effects of group and time (all > 0.42).
Wearing blue-light blocking lens had no clinically significant effect on adults' long-term contrast perception under scotopic or photopic conditions, or with glare.
评估两种不同程度的蓝光阻挡（BB）眼镜片在不同光照条件下对成年人对比度感知的长期影响。
总共招募了144名年龄为24.70（±4.32岁）的健康成年人参与这项随机对照试验。参与者被随机分为三组，并使用三种不同的眼镜片（15%BB：15%蓝光阻挡眼镜片；30%BB：30%蓝光阻挡眼镜片；RC：作为对照的普通透明镜片）。在使用的基线、1个月、3个月和6个月时，使用标准临床测试测量四种光照条件（暗视和明视，均有/无眩光）下的对比敏感度。对数对比敏感度函数下的面积（AULCSF）也被计算出来，作为他们在空间频率上整体对比敏感度的指标。
在任何光照条件下，三种类型的眼镜片之间的AULCSF均无显著差异（均>0.81）。四个时间点之间的AULSCF未发现统计学差异（均>0.39），组效应和时间效应之间无交互作用（均>0.42）。
佩戴蓝光阻挡镜片在暗视或明视条件下，或有眩光时，对成年人的长期对比度感知没有临床显著影响。
