Lindtjørn Bernt, Mitiku Demissew, Zidda Zillo, Yaya Yaliso
Centre for International Health, University of Bergen, Bergen, Norway.
Gidole Hospital, Gidole, Ethiopia.
PLoS One. 2017 Jan 3;12(1):e0169304. doi: 10.1371/journal.pone.0169304. eCollection 2017.
In a large population in Southwest Ethiopia (population 700,000), we carried out a complex set of interventions with the aim of reducing maternal mortality. This study evaluated the effects of several coordinated interventions to help improve effective coverage and reduce maternal deaths. Together with the Ministry of Health in Ethiopia, we designed a project to strengthen the health-care system. A particular emphasis was given to upgrade existing institutions so that they could carry out Basic (BEmOC) and Comprehensive Emergency Obstetric Care (CEmOC). Health institutions were upgraded by training non-clinical physicians and midwives by providing the institutions with essential and basic equipment, and by regular monitoring and supervision by staff competent in emergency obstetric work.
In this implementation study, the maternal mortality ratio (MMR) was the primary outcome. The study was carried out from 2010 to 2013 in three districts, and we registered 38,312 births. The MMR declined by 64% during the intervention period from 477 to 219 deaths per 100,000 live births (OR 0.46; 95% CI 0.24-0.88). The decline in MMR was higher for the districts with CEmOC, while the mean number of antenatal visits for each woman was 2.6 (Inter Quartile Range 2-4). The percentage of pregnant women who attended four or more antenatal controls increased by 20%, with the number of women who delivered at home declining by 10.5% (P<0.001). Similarly, the number of deliveries at health posts, health centres and hospitals increased, and we observed a decline in the use of traditional birth attendants. Households living near to all-weather roads had lower maternal mortality rates (MMR 220) compared with households without roads (MMR 598; OR 2.72 (95% CI 1.61-4.61)).
Our results show that it is possible to achieve substantial reductions in maternal mortality rates over a short period of time if the effective coverage of well-known interventions is implemented.
在埃塞俄比亚西南部的一个70万人口的大群体中,我们开展了一系列复杂的干预措施,旨在降低孕产妇死亡率。本研究评估了多项协调干预措施的效果,以帮助提高有效覆盖率并减少孕产妇死亡。我们与埃塞俄比亚卫生部共同设计了一个项目,以加强医疗保健系统。特别强调升级现有机构,使其能够开展基本产科急诊(BEmOC)和综合紧急产科护理(CEmOC)。通过培训非临床医生和助产士、为机构提供基本和基础设备以及由具备产科急诊工作能力的工作人员进行定期监测和监督,对医疗机构进行了升级。
在这项实施研究中,孕产妇死亡率(MMR)是主要结果。该研究于2010年至2013年在三个地区进行,我们记录了38312例分娩。在干预期间,孕产妇死亡率从每10万例活产477例死亡降至219例死亡,下降了64%(比值比0.46;95%置信区间0.24 - 0.88)。对于具备综合紧急产科护理的地区,孕产妇死亡率的下降幅度更大,而每位妇女的产前检查平均次数为2.6次(四分位间距2 - 4次)。进行四次或更多次产前检查的孕妇百分比增加了20%,在家分娩的妇女数量下降了10.5%(P<0.001)。同样,在卫生站、健康中心和医院分娩的数量增加了,并且我们观察到传统接生员的使用减少了。与没有道路的家庭(孕产妇死亡率598)相比,居住在全天候道路附近的家庭孕产妇死亡率较低(孕产妇死亡率220;比值比2.72(95%置信区间1.61 - 4.61))。
我们的结果表明,如果实施知名干预措施的有效覆盖,有可能在短时间内大幅降低孕产妇死亡率。