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术前门静脉栓塞后肝细胞癌完全坏死:一例报告

Complete necrosis of hepatocellular carcinoma after preoperative portal vein embolization: a case report.

作者信息

El Bacha H, Salihoun M, Kabbaj N, Benkabbou A

机构信息

Faculté de médecine et de pharmacie de Rabat, Mohammed V University, Rabat, Morocco.

Explorations Fonctionnelles Digestives, Ibn Sina Hospital, Rabat, Morocco.

出版信息

J Med Case Rep. 2017 Jan 4;11(1):7. doi: 10.1186/s13256-016-1160-8.

Abstract

BACKGROUND

Hepatocellular carcinoma has a poor prognosis; few patients can undergo surgical curative treatment according to Barcelona Clinic Liver Cancer guidelines. Progress in surgical techniques has led to operations for more patients outside these guidelines. Our case shows a patient with intermediate stage hepatocellular carcinoma presenting a good outcome after curative treatment.

CASE PRESENTATION

We report the case of an 80-year-old Moroccan man, who was positive for hepatitis c virus, presenting an intermediate stage hepatocellular carcinoma (three lesions between 20 and 60 mm). He presented a complete tumor necrosis after portal vein embolization and achieved 24-month disease-free survival after surgery.

CONCLUSIONS

Perioperative care in liver surgery and multidisciplinary discussion can help to extend indications for liver resection for hepatocellular carcinoma outside European Association for the Study of the Liver/American Association for the Study of Liver Diseases recommendations and offer a curative approach to selected patients with intermediate and advanced stage hepatocellular carcinoma.

摘要

背景

肝细胞癌预后较差;根据巴塞罗那临床肝癌指南,很少有患者能够接受手术根治性治疗。手术技术的进步使得更多不在这些指南范围内的患者能够接受手术。我们的病例显示一名中期肝细胞癌患者在接受根治性治疗后取得了良好的效果。

病例报告

我们报告一例80岁摩洛哥男性病例,该患者丙型肝炎病毒检测呈阳性,患有中期肝细胞癌(三个病灶,直径在20至60毫米之间)。门静脉栓塞后肿瘤出现完全坏死,术后实现了24个月无病生存。

结论

肝脏手术的围手术期护理和多学科讨论有助于扩大欧洲肝脏研究协会/美国肝病研究协会建议范围之外的肝细胞癌肝切除适应症,并为部分中晚期肝细胞癌患者提供根治性治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab58/5210282/18055c8a4c1c/13256_2016_1160_Fig1_HTML.jpg

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