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你所不知道的可能会伤害你:女性希望医生告知她们的关于化疗对记忆及酒精反应的副作用

What You Do Not Know Could Hurt You: What Women Wish Their Doctors Had Told Them About Chemotherapy Side Effects on Memory and Response to Alcohol.

作者信息

Couvertier-Lebron Carmen E, Dove Rachel, Acevedo Summer F

机构信息

Psychology Program, Ponce School of Medicine and Health Sciences, Ponce, Puerto Rico.

Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA.

出版信息

Breast Cancer (Auckl). 2016 Dec 20;10:229-238. doi: 10.4137/BCBCR.S38389. eCollection 2016.

Abstract

For many patients, a cancer diagnosis is followed by chemotherapy treatment, which works by attacking cells that are growing and dividing throughout the body. Although cancer cells grow and divide more quickly than healthy cells, both are targets. The loss of healthy cells is associated with side effects, such as memory loss and altered response to a variety of food and drugs. In this pilot study, we use the "Survey of female cancer treatments, effects on memory and alcohol awareness" to explore trends in female experience and awareness of side effects associated with chemotherapy. We examined 79 female cancer patients, 46 Spanish-speaking women in Puerto Rico and 33 English-speaking women in the continental United States, and compared the rates of a reported memory loss or an altered ethanol response following chemotherapy, whether or not potential side effects were discussed with a medical professional, and whether they experienced changes in alcohol consumption after treatment. A majority of participants reported having experienced short-term memory loss postchemotherapy. Changes in response to alcohol and an altered sensitivity to alcohol were also reported by 25%-47% of the respondents. Additionally, more than half of all female cancer patients reported that they wished they would have received information on the side effects of chemotherapy and secondary medications prior to treatment. The survey results suggest that medical professionals are not adequately informing women of common, potentially harmful side effects of chemotherapy. Women do wish to be more educated about potential side effects related to memory and alcohol and be given the opportunity to discuss potential outcomes with a medical professional prior to treatment to reduce the negative impact of treatment-related side effects on posttreatment quality of life.

摘要

对于许多患者来说,癌症诊断后会接受化疗,化疗的作用是攻击全身正在生长和分裂的细胞。尽管癌细胞比健康细胞生长和分裂得更快,但两者都是攻击目标。健康细胞的损失会带来副作用,如记忆力减退以及对各种食物和药物的反应改变。在这项初步研究中,我们使用“女性癌症治疗、对记忆和酒精认知的影响调查”来探究女性在化疗相关副作用方面的经历和认知趋势。我们研究了79名女性癌症患者,其中46名是波多黎各讲西班牙语的女性,33名是美国大陆讲英语的女性,并比较了化疗后报告的记忆力减退或乙醇反应改变的发生率,无论是否与医疗专业人员讨论过潜在的副作用,以及她们在治疗后饮酒量是否发生变化。大多数参与者报告称化疗后经历了短期记忆力减退。25%-47%的受访者还报告了对酒精反应的变化以及对酒精敏感度的改变。此外,超过一半的女性癌症患者报告称,她们希望在治疗前就收到有关化疗和辅助药物副作用的信息。调查结果表明,医疗专业人员没有充分告知女性化疗常见的、潜在有害的副作用。女性确实希望更多地了解与记忆和酒精相关的潜在副作用,并在治疗前有机会与医疗专业人员讨论潜在结果,以减少治疗相关副作用对治疗后生活质量的负面影响。

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