Michelucci A, Padeletti L, Mezzani A, Giovannini T, Miceli M, Cupelli V, Musante R
Cardiology Unit, University of Florence, Italy.
Cardiology. 1989;76(4):270-3. doi: 10.1159/000174503.
In 22 patients (age range 13-40 years) with Wolff-Parkinson-White ECG pattern without evidence of associated cardiomyopathy we measured the anterograde effective refractory period of the accessory pathway (ERP-AP) by extrastimulus method (at twice diastolic threshold) during atrial pacing (100/min). The ERP-AP range was 220-480 ms. There was a significant direct correlation between age and ERP-AP (r = 0.50, p less than 0.01). An ERP-AP less than or equal to 250 ms was found in 4 patients (age less than or equal to 23 years). This is noteworthy in the light of reports that, over the years: (1) typical Wolff-Parkinson-White ECG signs can disappear and (2) the frequency of tachycardic episodes decreases. Our data suggest a lower risk of high ventricular rates during atrial fibrillation with increasing age.
在22例（年龄范围13 - 40岁）心电图呈预激综合征模式且无相关心肌病证据的患者中，我们在心房起搏（100次/分钟）期间通过额外刺激法（在舒张阈值两倍时）测量了旁路的前向有效不应期（ERP - AP）。ERP - AP范围为220 - 480毫秒。年龄与ERP - AP之间存在显著的直接相关性（r = 0.50，p < 0.01）。4例患者（年龄≤23岁）的ERP - AP≤250毫秒。鉴于多年来的报道：（1）典型的预激综合征心电图征象可能消失，以及（2）心动过速发作频率降低，这一点值得注意。我们的数据表明，随着年龄增长，房颤时心室率过高的风险较低。
