• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童锁骨骨髓炎1例罕见病例及文献复习

A Rare Case of Clavicle Osteomyelitis in a Child and Literature Review.

作者信息

Chrysochoou Elisavet-Anna, Antachopoulos Charalampos, Badekas Konstantinos, Roilides Emmanuel

机构信息

Infectious Diseases Unit, 3rd Department of Pediatrics, Medical Faculty, Aristotle University School of Health Sciences, Hippokration Hospital, Thessaloniki, Greece.

Department of Pediatrics, General Hospital of Serres, Serres, Central Macedonia, Greece.

出版信息

Case Rep Pediatr. 2016;2016:8252318. doi: 10.1155/2016/8252318. Epub 2016 Dec 5.

DOI:10.1155/2016/8252318
PMID:28050301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5165129/
Abstract

Acute clavicle osteomyelitis in children is rare representing <3% of osteomyelitis cases. We treated a 12-year-old boy who presented with acute pain in the right clavicle and high fever for 4 days. MRI showed abnormal signal in the right clavicle with periosteal reaction. isolated from blood was susceptible to methicillin, clindamycin, and macrolides. Clindamycin was given intravenously for 3 wks and orally for another 3 wks with no recurrence. We reviewed clavicle osteomyelitis cases in children searching PubMed English literature. From a total of 89 studies retrieved, only 6 fulfilled the criteria and were analyzed. Sixteen patients (56% female) were included with a median age of 9 yrs (range 2 wks-16 yrs). Osteomyelitis was hematogenous in most cases, with being the most frequent cause, isolated from either blood or tissue. Symptoms included fever, swelling, and localized bone tenderness. Antimicrobial therapy lasted for 4-12 weeks (median 7.5). Three patients required drainage or curettage. Recurrence occurred in 1/16 cases (6.2%) and persistence of symptoms occurred to 2/16 cases (12.5%) reported before 90s with unknown antimicrobial susceptibility of the pathogen. Acute clavicle osteomyelitis mainly affects older children and has generally good prognosis. is most commonly implicated and surgery may be needed.

摘要

儿童急性锁骨骨髓炎较为罕见,占骨髓炎病例的比例不到3%。我们治疗了一名12岁男孩,他右锁骨急性疼痛并高热4天。MRI显示右锁骨信号异常并伴有骨膜反应。从血液中分离出的病原体对甲氧西林、克林霉素和大环内酯类药物敏感。静脉注射克林霉素3周,随后口服3周,无复发。我们检索了PubMed英文文献中的儿童锁骨骨髓炎病例。在检索到的89项研究中,只有6项符合标准并进行了分析。纳入了16例患者(56%为女性),中位年龄为9岁(范围为2周 - 16岁)。大多数情况下骨髓炎是血源性的, 是最常见的病因,从血液或组织中分离得到。症状包括发热、肿胀和局部骨压痛。抗菌治疗持续4 - 12周(中位7.5周)。3例患者需要引流或刮除术。1/16例(6.2%)出现复发,2/16例(12.5%)出现症状持续,这些是90年代之前报道的病例,病原体的抗菌药敏情况未知。急性锁骨骨髓炎主要影响大龄儿童,总体预后良好。 最常涉及,可能需要手术治疗。 (注:原文中部分处有缺失信息,用“ ”表示)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9646/5165129/86b9588e17c7/CRIPE2016-8252318.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9646/5165129/86b9588e17c7/CRIPE2016-8252318.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9646/5165129/86b9588e17c7/CRIPE2016-8252318.001.jpg

相似文献

1
A Rare Case of Clavicle Osteomyelitis in a Child and Literature Review.儿童锁骨骨髓炎1例罕见病例及文献复习
Case Rep Pediatr. 2016;2016:8252318. doi: 10.1155/2016/8252318. Epub 2016 Dec 5.
2
Acute staphylococcal osteomyelitis of the clavicle.锁骨急性葡萄球菌骨髓炎
J Pediatr Orthop. 1997 Jul-Aug;17(4):467-9.
3
A rare case of osteomyelitis of the clavicle in a child due to Group A streptococcal infection.一例因A组链球菌感染导致儿童锁骨骨髓炎的罕见病例。
BMJ Case Rep. 2019 Apr 11;12(4):e227090. doi: 10.1136/bcr-2018-227090.
4
Acute osteomyelitis in children: the pathogenesis revisited?儿童急性骨髓炎:重新审视发病机制?
Orthop Traumatol Surg Res. 2010 May;96(3):268-75. doi: 10.1016/j.otsr.2009.12.012.
5
Osteomyelitis of the clavicle.锁骨骨髓炎
Arch Otolaryngol Head Neck Surg. 1988 Sep;114(9):1000-2. doi: 10.1001/archotol.1988.01860210066017.
6
Clinical characteristics and treatment of clavicular osteomyelitis: a systematic review with pooled analysis of 294 reported cases.锁骨骨髓炎的临床特征和治疗:一项系统评价和 294 例报告病例的汇总分析。
J Shoulder Elbow Surg. 2019 Jul;28(7):1411-1421. doi: 10.1016/j.jse.2018.11.071. Epub 2019 Feb 28.
7
Chronic Osteomyelitis of Clavicle in a Neonate: Report of Morbid Complication of Adjoining MRSA Abscess.新生儿锁骨慢性骨髓炎:伴发耐甲氧西林金黄色葡萄球菌脓肿的严重并发症报告
Case Rep Pediatr. 2016;2016:3032518. doi: 10.1155/2016/3032518. Epub 2016 Mar 8.
8
Antibiotic Treatment and Surgery for Acute Hematogenous Calcaneal Osteomyelitis of Childhood.儿童急性血源性跟骨骨髓炎的抗生素治疗与手术治疗
J Foot Ankle Surg. 2015 Sep-Oct;54(5):840-3. doi: 10.1053/j.jfas.2015.01.006. Epub 2015 Apr 22.
9
[Chronic osteomyelitis of the clavicle].
Klin Padiatr. 1989 May-Jun;201(3):199-201. doi: 10.1055/s-2007-1025302.
10
Favorable outcome of extended curettage for the treatment of unifocal chronic sclerosing osteomyelitis of clavicle: a case series.扩展刮除术治疗单一病灶慢性硬化性骨髓炎的疗效:病例系列研究。
J Shoulder Elbow Surg. 2020 May;29(5):954-960. doi: 10.1016/j.jse.2019.08.020. Epub 2019 Oct 28.

引用本文的文献

1
Complete Clavicular Resorption after Clavicular osteomyelitis with no functional deficit at 13-year follow-up: A Case Report.锁骨骨髓炎后锁骨完全吸收,13年随访无功能缺陷:一例报告
J Orthop Case Rep. 2025 Jul;15(7):84-87. doi: 10.13107/jocr.2025.v15.i07.5776.
2
A Child With Acute Hematogenous Osteomyelitis of the Distal Fibula and Infective Endocarditis.一名患有远端腓骨急性血源性骨髓炎和感染性心内膜炎的儿童。
Cureus. 2023 Feb 24;15(2):e35429. doi: 10.7759/cureus.35429. eCollection 2023 Feb.
3
A Rare Presentation of Brodie Abscess in the Clavicle.

本文引用的文献

1
Acute osteomyelitis in children.儿童急性骨髓炎
N Engl J Med. 2014 Jan 23;370(4):352-60. doi: 10.1056/NEJMra1213956.
2
Childhood osteomyelitis: imaging characteristics.儿童骨髓炎:影像学特征。
Insights Imaging. 2012 Oct;3(5):519-33. doi: 10.1007/s13244-012-0186-8. Epub 2012 Aug 10.
3
Management of acute hematogenous osteomyelitis in children.儿童急性血源性骨髓炎的治疗。
锁骨布氏脓肿的罕见表现。
J Am Acad Orthop Surg Glob Res Rev. 2021 Apr 13;5(4):e20.00249. doi: 10.5435/JAAOSGlobal-D-20-00249.
4
Similarities and Differences between Clavicular Bacterial Osteomyelitis and Nonbacterial Osteitis: Comparisons of 327 Reported Cases.锁骨细菌性骨髓炎与非细菌性骨髓炎的异同:327 例报告病例比较。
J Immunol Res. 2021 Jan 26;2021:4634505. doi: 10.1155/2021/4634505. eCollection 2021.
Expert Rev Anti Infect Ther. 2010 Feb;8(2):175-81. doi: 10.1586/eri.09.130.
4
Postnatal growth of the clavicle: birth to 18 years of age.锁骨的出生后生长:从出生到18岁
J Pediatr Orthop. 2009 Dec;29(8):937-43. doi: 10.1097/BPO.0b013e3181c11992.
5
Imaging of osteomyelitis: current concepts.骨髓炎的影像学:当前概念
Infect Dis Clin North Am. 2006 Dec;20(4):789-825. doi: 10.1016/j.idc.2006.09.009.
6
Pediatric orthopedic infections: early detection and treatment.小儿骨科感染:早期检测与治疗
Pediatr Ann. 2006 Feb;35(2):112-22. doi: 10.3928/0090-4481-20060201-11.
7
Bone and joint infections in children.儿童骨与关节感染
Pediatr Clin North Am. 2005 Jun;52(3):779-94, vi. doi: 10.1016/j.pcl.2005.02.005.
8
Osteomyelitis.骨髓炎
Lancet. 2004;364(9431):369-79. doi: 10.1016/S0140-6736(04)16727-5.
9
Ultrasonography of musculoskeletal infections in children.儿童肌肉骨骼感染的超声检查
Eur Radiol. 2004 Mar;14 Suppl 4:L65-77. doi: 10.1007/s00330-003-2029-y.
10
Shorter courses of parenteral antibiotic therapy do not appear to influence response rates for children with acute hematogenous osteomyelitis: a systematic review.短期胃肠外抗生素治疗似乎不会影响急性血源性骨髓炎患儿的反应率:一项系统评价。
BMC Infect Dis. 2002 Aug 14;2:16. doi: 10.1186/1471-2334-2-16.