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Am J Surg Pathol. 2012 Aug;36(8):1150-7. doi: 10.1097/PAS.0b013e31825b9914.
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Pure vulvar Langerhans cell histiocytosis: a case report and literature review.
Eur J Gynaecol Oncol. 2009;30(6):691-4.
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Spitz nevus of the genital mucosa.生殖器黏膜 Spitz 痣。
Indian J Dermatol Venereol Leprol. 2009 Mar-Apr;75(2):167-9. doi: 10.4103/0378-6323.48663.
6
An 'eruptive' variant of juvenile xanthogranuloma associated with langerhans cell histiocytosis.与朗格汉斯细胞组织细胞增多症相关的幼年性黄色肉芽肿的“爆发性”变体。
J Cutan Pathol. 2008 Oct;35 Suppl 1:50-4. doi: 10.1111/j.1600-0560.2007.00959.x.
7
Juvenile xanthogranuloma in childhood and adolescence: a clinicopathologic study of 129 patients from the kiel pediatric tumor registry.儿童和青少年期幼年性黄色肉芽肿：来自基尔儿科肿瘤登记处129例患者的临床病理研究
Am J Surg Pathol. 2005 Jan;29(1):21-8. doi: 10.1097/01.pas.0000147395.01229.06.
8
Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations.174例有皮肤及皮肤外表现的青少年黄色肉芽肿的临床病理研究：发病年龄在20岁以内者
Am J Surg Pathol. 2003 May;27(5):579-93. doi: 10.1097/00000478-200305000-00003.
9
Adult xanthogranuloma of the vulva: case report and review.
Pathology. 2002 Feb;34(1):86-7. doi: 10.1080/00313020120105688.
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[Congenital manifestations of juvenile xanthogranuloma (large nodular form)].
Hautarzt. 2000 Jun;51(6):423-6. doi: 10.1007/s001050051145.

一名10岁女童外阴部的幼年性黄色肉芽肿

Juvenile Xanthogranuloma in Vulva of a 10-Year-Old Child.

作者信息

Gupta Barkha, Yadav Surekha, Khurana Nita, Sharma Manish

机构信息

Senior Resident, Department of Pathology, Maulana Azad Medical College , New Delhi, India .

Professor, Department of Pathology, Maulana Azad Medical College , New Delhi, India .

出版信息

J Clin Diagn Res. 2016 Nov;10(11):ED21-ED22. doi: 10.7860/JCDR/2016/22266.8930. Epub 2016 Nov 1.

DOI:10.7860/JCDR/2016/22266.8930
PMID:28050386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5198339/
Abstract

A 10-year-old child presented with asymptomatic, well-circumscribed nodule in the vulva. Excision biopsy showed features of classic Juvenile Xanthogranuloma (JXG) which is a rare benign disorder of non-langerhans' cell group of histiocytic proliferative diseases. The presentation of this lesion as vulval nodule is extremely rare and the extensive literature search revealed only handful of cases of vulval xanthogranuloma that too in an adult age group. The lesion is however prognostically favourable and should be kept in mind as one of the differential diagnosis of the vulval nodule.

摘要

一名10岁儿童在外阴出现无症状、边界清晰的结节。切除活检显示为典型幼年性黄色肉芽肿（JXG）的特征，这是一种罕见的非朗格汉斯细胞组织细胞增生性疾病的良性病症。这种病变表现为外阴结节极为罕见，广泛的文献检索仅发现少数外阴黄色肉芽肿病例，且均为成年年龄组。然而，该病变预后良好，应作为外阴结节的鉴别诊断之一予以考虑。