一名10岁女童外阴部的幼年性黄色肉芽肿
Juvenile Xanthogranuloma in Vulva of a 10-Year-Old Child.
作者信息
Gupta Barkha, Yadav Surekha, Khurana Nita, Sharma Manish
机构信息
Senior Resident, Department of Pathology, Maulana Azad Medical College , New Delhi, India .
Professor, Department of Pathology, Maulana Azad Medical College , New Delhi, India .
出版信息
J Clin Diagn Res. 2016 Nov;10(11):ED21-ED22. doi: 10.7860/JCDR/2016/22266.8930. Epub 2016 Nov 1.
Abstract
A 10-year-old child presented with asymptomatic, well-circumscribed nodule in the vulva. Excision biopsy showed features of classic Juvenile Xanthogranuloma (JXG) which is a rare benign disorder of non-langerhans' cell group of histiocytic proliferative diseases. The presentation of this lesion as vulval nodule is extremely rare and the extensive literature search revealed only handful of cases of vulval xanthogranuloma that too in an adult age group. The lesion is however prognostically favourable and should be kept in mind as one of the differential diagnosis of the vulval nodule.
摘要
一名10岁儿童在外阴出现无症状、边界清晰的结节。切除活检显示为典型幼年性黄色肉芽肿（JXG）的特征，这是一种罕见的非朗格汉斯细胞组织细胞增生性疾病的良性病症。这种病变表现为外阴结节极为罕见，广泛的文献检索仅发现少数外阴黄色肉芽肿病例，且均为成年年龄组。然而，该病变预后良好，应作为外阴结节的鉴别诊断之一予以考虑。
相似文献
1
Juvenile Xanthogranuloma in Vulva of a 10-Year-Old Child.一名10岁女童外阴部的幼年性黄色肉芽肿
J Clin Diagn Res. 2016 Nov;10(11):ED21-ED22. doi: 10.7860/JCDR/2016/22266.8930. Epub 2016 Nov 1.
2
Nonlipidized juvenile xanthogranuloma: an unusual variant with a potential diagnostic pitfall.非脂质化幼年性黄色肉芽肿：一种具有潜在诊断陷阱的不寻常变体。
Int J Pediatr Otorhinolaryngol. 2012 Feb;76(2):295-9. doi: 10.1016/j.ijporl.2011.11.010. Epub 2011 Dec 26.
3
Mammary presentation of adult-type "juvenile" xanthogranuloma.成人型“青少年”黄色肉芽肿的乳腺表现
Am J Surg Pathol. 2005 Jun;29(6):827-31. doi: 10.1097/01.pas.0000153469.98797.57.
4
Oral juvenile xanthogranuloma in a child: Clinical, histological and immunohistochemical profile of a rare entity.儿童口腔幼年性黄色肉芽肿：一种罕见疾病的临床、组织学和免疫组化特征
J Cutan Pathol. 2018 Jul;45(7):515-521. doi: 10.1111/cup.13152. Epub 2018 May 9.
5
Juvenile xanthogranuloma in childhood and adolescence: a clinicopathologic study of 129 patients from the kiel pediatric tumor registry.儿童和青少年期幼年性黄色肉芽肿：来自基尔儿科肿瘤登记处129例患者的临床病理研究
Am J Surg Pathol. 2005 Jan;29(1):21-8. doi: 10.1097/01.pas.0000147395.01229.06.
6
Cytological diagnosis of juvenile xanthogranuloma: A rare histiocytic disorder.青少年黄色肉芽肿的细胞学诊断：一种罕见的组织细胞疾病。
Diagn Cytopathol. 2020 Jan;48(1):66-70. doi: 10.1002/dc.24310. Epub 2019 Aug 20.
7
Juvenile xanthogranuloma of the oral cavity in children: a clinicopathologic study.儿童口腔幼年性黄色肉芽肿：一项临床病理研究。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Sep;94(3):345-52. doi: 10.1067/moe.2002.122340.
8
Giant Juvenile Xanthogranuloma: Case Report, Literature Review, and Algorithm for Classification.巨细胞幼年黄色肉芽肿：病例报告、文献回顾及分类算法。
J Cutan Med Surg. 2018 Sep/Oct;22(5):488-494. doi: 10.1177/1203475418777734. Epub 2018 May 21.
9
Solitary intracerebral juvenile xanthogranuloma. Case report and review of the literature.孤立性脑内青少年黄色肉芽肿。病例报告及文献复习
Pediatr Neurosurg. 1997 Jun;26(6):315-21. doi: 10.1159/000121212.
10
The epidemiology, clinical characteristics, histopathology and management of juvenile- and adult-onset corneoscleral limbus xanthogranuloma.青少年及成人期角膜缘黄色瘤的流行病学、临床特征、组织病理学及治疗
Graefes Arch Clin Exp Ophthalmol. 2016 Mar;254(3):413-20. doi: 10.1007/s00417-015-3261-2. Epub 2016 Jan 21.
引用本文的文献
1
Juvenile Xanthogranuloma as Differential Diagnosis of a Vulvar Mass: A Case Report.幼年性黄色肉芽肿作为外阴肿物的鉴别诊断：一例报告
European J Pediatr Surg Rep. 2022 Apr 19;10(1):e25-e29. doi: 10.1055/s-0042-1743159. eCollection 2022 Jan.
2
Anogenital Papular Lesions in Children Five Year Old and Younger: Gender Differences.儿童五岁及以下肛门生殖器丘疹性病变：性别差异。
Med Arch. 2020 Feb;74(1):28-33. doi: 10.5455/medarh.2020.74.28-33.
本文引用的文献
1
Vulvar necrobiotic xanthogranuloma.外阴坏死性黄色肉芽肿
J Am Acad Dermatol. 2014 Dec;71(6):e247-8. doi: 10.1016/j.jaad.2014.04.039. Epub 2014 Nov 15.
2
Vulvar embryonal rhabdomyosarcoma: a case report.外阴胚胎型横纹肌肉瘤：一例报告。
J Pediatr Urol. 2013 Aug;9(4):e144-6. doi: 10.1016/j.jpurol.2013.02.016. Epub 2013 Apr 19.
3
Use of the JL1 epitope, which encompasses the nonglycosylation site of CD43, as a marker of immature/neoplastic Langerhans cells.使用 JL1 表位（包含 CD43 的非糖基化位点）作为不成熟/肿瘤性朗格汉斯细胞的标志物。
Am J Surg Pathol. 2012 Aug;36(8):1150-7. doi: 10.1097/PAS.0b013e31825b9914.
4
Pure vulvar Langerhans cell histiocytosis: a case report and literature review.
Eur J Gynaecol Oncol. 2009;30(6):691-4.
5
Spitz nevus of the genital mucosa.生殖器黏膜 Spitz 痣。
Indian J Dermatol Venereol Leprol. 2009 Mar-Apr;75(2):167-9. doi: 10.4103/0378-6323.48663.
6
An 'eruptive' variant of juvenile xanthogranuloma associated with langerhans cell histiocytosis.与朗格汉斯细胞组织细胞增多症相关的幼年性黄色肉芽肿的“爆发性”变体。
J Cutan Pathol. 2008 Oct;35 Suppl 1:50-4. doi: 10.1111/j.1600-0560.2007.00959.x.
7
Juvenile xanthogranuloma in childhood and adolescence: a clinicopathologic study of 129 patients from the kiel pediatric tumor registry.儿童和青少年期幼年性黄色肉芽肿：来自基尔儿科肿瘤登记处129例患者的临床病理研究
Am J Surg Pathol. 2005 Jan;29(1):21-8. doi: 10.1097/01.pas.0000147395.01229.06.
8
Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations.174例有皮肤及皮肤外表现的青少年黄色肉芽肿的临床病理研究：发病年龄在20岁以内者
Am J Surg Pathol. 2003 May;27(5):579-93. doi: 10.1097/00000478-200305000-00003.
9
Adult xanthogranuloma of the vulva: case report and review.
Pathology. 2002 Feb;34(1):86-7. doi: 10.1080/00313020120105688.
10
[Congenital manifestations of juvenile xanthogranuloma (large nodular form)].
Hautarzt. 2000 Jun;51(6):423-6. doi: 10.1007/s001050051145.
Zotero 插件