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妊娠合并绒毛膜癌伴颅内转移

Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis.

作者信息

Siwatch Sujata, Suri Vanita, Sikka Pooja, Aggarwal Neelam, Chopra Seema

机构信息

Assistant Professor, Department of Obstetrics and Gynecology, PGIMER , Chandigarh, India .

Professor, Department of Obstetrics and Gynecology, PGIMER , Chandigarh, India .

出版信息

J Clin Diagn Res. 2016 Nov;10(11):QD01-QD03. doi: 10.7860/JCDR/2016/19344.8769. Epub 2016 Nov 1.

DOI:10.7860/JCDR/2016/19344.8769
PMID:28050451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5198404/
Abstract

Choriocarcinoma presents usually as persistent trophoblastic disease, with prognosis worsening with duration from antecedent pregnancy. We present a unique case of a woman with choriocarcinoma who presented in the third trimester of pregnancy with eclampsia. She was managed with magnesium sulphate and underwent a caesarean section. However, she developed seizures in the post-partum period that were further investigated and attributed to intracranial metastatic lesions of Gestational Trophoblastic Neoplasia (GTN). We discussed the diagnostic challenge in this rare case of GTN and the grave potential it can have in such a presentation, as in our patient.

摘要

绒毛膜癌通常表现为持续性滋养细胞疾病,其预后随着距前次妊娠时间的延长而恶化。我们报告了一例独特的绒毛膜癌病例,该患者在妊娠晚期出现子痫。她接受了硫酸镁治疗并进行了剖宫产。然而,她在产后出现癫痫发作,经进一步检查发现是由妊娠滋养细胞肿瘤(GTN)的颅内转移灶所致。我们讨论了这例罕见的GTN病例的诊断挑战,以及它在这种表现形式下(如我们的患者)可能具有的严重潜在风险。

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