[A study on the safety of four vaccines of children EPI at the same time and the results of the immunological responses after vaccination].

The safety of the synthetic immunization of BCG, DPT, TOPV and MV and the results of studying on the immunological responses were reported. 337 preliminary immunized children of 3-24 month-age were voluntarily classified. The clinical reactions and the serological results of vaccination were systematically analyzed. It was identified that the effect of the synthetic immunization of four vaccines or three vaccines was similar to that of the individual immunization, i.e., the clinical reactions were slight and the effect was good after immunization. It was confirmed that the synthetic immunization could simplify the procedure of immunization and save manpower and cost. And it could solve the contradiction of the time space of vaccination, increase the vaccination coverage. It had comparative high social and economic benefit and fit for spreading in remote mountain area and minority nationality areas.