Li L
Zhonghua Liu Xing Bing Xue Za Zhi. 1989 Aug;10(4):215-8.
The safety of the synthetic immunization of BCG, DPT, TOPV and MV and the results of studying on the immunological responses were reported. 337 preliminary immunized children of 3-24 month-age were voluntarily classified. The clinical reactions and the serological results of vaccination were systematically analyzed. It was identified that the effect of the synthetic immunization of four vaccines or three vaccines was similar to that of the individual immunization, i.e., the clinical reactions were slight and the effect was good after immunization. It was confirmed that the synthetic immunization could simplify the procedure of immunization and save manpower and cost. And it could solve the contradiction of the time space of vaccination, increase the vaccination coverage. It had comparative high social and economic benefit and fit for spreading in remote mountain area and minority nationality areas.
报告了卡介苗、百白破、脊髓灰质炎口服疫苗和麻疹疫苗联合免疫的安全性及免疫应答研究结果。对337名3至24月龄初免儿童进行了自愿分组，系统分析了疫苗接种的临床反应和血清学结果。结果表明，四种疫苗或三种疫苗联合免疫的效果与单独免疫相似，即临床反应轻微，免疫后效果良好。证实联合免疫可简化免疫程序，节省人力和成本，还可解决预防接种的时空矛盾，提高接种率，具有较高的社会和经济效益，适合在偏远山区和少数民族地区推广。
