Guyer B, Atangana S
Bull World Health Organ. 1977;55(5):633-42.
The Yaoundé multiple-antigen childhood immunization programme began in November 1975, making it one of the first expanded programmes on immunization operational in Africa. During the first 9 months, more than 22 000 children were immunized against poliomyelitis, measles, tuberculosis, smallpox, whooping cough, tetanus, and diphtheria. Evaluation of the programme showed the following rates of immunization coverage in the target population; 30% for DPT (one dose or more), 27% for poliomyelitis (one dose or more), 27% for BCG, 33% for measles, and 20% for smallpox. Eighty per cent of children received the correct vaccines for their age and vaccination status. Seroconversion to measles vaccine was 89% in those over 12 months of age but only 50% in those between 6 and 11 months of age. The major factor in low immunization coverage was felt to be inadequate publicity. The cost of the programme was estimated to be US $10 920. The cost of immunizing a child completely was estimated at US $1.90. Some logistic problems encountered during this initial year of operation are discussed.
雅温得儿童多抗原免疫规划于1975年11月启动,使其成为非洲最早实施的扩大免疫规划之一。在最初的9个月里,超过22000名儿童接种了脊髓灰质炎、麻疹、结核病、天花、百日咳、破伤风和白喉疫苗。对该规划的评估显示,目标人群的免疫接种覆盖率如下:白喉、百日咳、破伤风三联疫苗(一剂或更多剂)为30%,脊髓灰质炎(一剂或更多剂)为27%,卡介苗为27%,麻疹为33%,天花为20%。80%的儿童根据其年龄和接种状况接种了正确的疫苗。12个月以上儿童麻疹疫苗的血清转化率为89%,但6至11个月龄儿童的血清转化率仅为50%。免疫接种覆盖率低的主要因素被认为是宣传不足。该规划的成本估计为10920美元。完全为一名儿童接种疫苗的成本估计为1.90美元。本文讨论了在运营的第一年遇到的一些后勤问题。