Ali Irfan, Patthi Basavaraj, Singla Ashish, Gupta Ritu, Dhama Kuldeep, Niraj Lav Kumar, Kumar Jishnu Krishna, Prasad Monika
Tutor, Department of Public Health Dentistry, D.J. College of Dental Sciences and Research , Ghaziabad, Uttar Pradesh, India .
Professor and Head, Department of Public Health Dentistry, D.J. College of Dental Sciences and Research , Ghaziabad, Uttar Pradesh, India .
J Clin Diagn Res. 2016 Nov;10(11):ZE01-ZE06. doi: 10.7860/JCDR/2016/19439.8790. Epub 2016 Nov 1.
Oral contraceptives are one of the risk factors for gingival disease. Oral contraceptives can affect the proliferation of cell, growth and differentiation of tissues in the periodontium. Nowadays recent research has suggested that the newer generation oral contraceptives have less influence on gingival diseases.
The purpose of this study was to systematically review the effect of oral contraceptives on periodontium.
A literature review was performed; PubMed, PubMed Central and Cochrane Library, Embase, Google Scholar were searched from 1970 up to December 2015 to identify appropriate studies.
Out of the total 94 titles appeared 13 articles fulfilled the criteria and were selected for the review. Two articles which were hand searched and one article which was through e-mail was also included. The hormones progesterone and estrogen have direct impact on immune system of the body and thus, affect the pattern and rate of collagen production in the gingiva. Furthermore, the review also shows that longer duration usage of oral contraceptive could lead to poorer oral hygiene status, gingival inflammation and increased susceptibility to periodontal disease.
There are relatively few studies evaluating the effect of oral contraceptives on periodontium. It was found that oral contraceptives have a marked effect on periodontium. The gingival changes after use of oral contraceptives are pronounced in the first few months and with the passage of time these changes get enhanced.
口服避孕药是牙龈疾病的危险因素之一。口服避孕药会影响牙周组织中细胞的增殖、组织的生长和分化。如今,最新研究表明新一代口服避孕药对牙龈疾病的影响较小。
本研究的目的是系统评价口服避孕药对牙周组织的影响。
进行文献综述;检索了1970年至2015年12月期间的PubMed、PubMed Central和Cochrane图书馆、Embase、谷歌学术,以确定合适的研究。
在总共94篇标题中,有13篇文章符合标准并被选入综述。还纳入了两篇手动检索的文章和一篇通过电子邮件获取的文章。孕激素和雌激素对人体免疫系统有直接影响,因此会影响牙龈中胶原蛋白的产生模式和速率。此外,综述还表明,长期使用口服避孕药可能导致口腔卫生状况较差、牙龈炎症以及对牙周疾病的易感性增加。
评估口服避孕药对牙周组织影响的研究相对较少。发现口服避孕药对牙周组织有显著影响。使用口服避孕药后的牙龈变化在最初几个月较为明显,随着时间的推移这些变化会加剧。