Wang Jianguang, Lee Tae Sup, Zhang Zhe, Tung Ching-Hsuan
Molecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, 413 East 69th Street, New York, NY, 10065, USA.
Current address: School of Chemical and Environmental Engineering, Anyang Institute of Technology, West of HuangHe Road, Anyang, 455000, PR China.
Chem Asian J. 2017 Feb 16;12(4):397-400. doi: 10.1002/asia.201601659. Epub 2017 Jan 19.
A bioluminogenic probe based on luciferin was designed and synthesized to monitor tyrosinase activity. This probe was efficient in assessing tyrosinase activity in a buffered aqueous solution and in measuring endogenous tyrosinase activity in melanoma cells.
设计并合成了一种基于荧光素的生物发光探针，用于监测酪氨酸酶活性。该探针在缓冲水溶液中评估酪氨酸酶活性以及测量黑色素瘤细胞中的内源性酪氨酸酶活性方面表现高效。
