Hart A, Smith J M, Skeans M A, Gustafson S K, Stewart D E, Cherikh W S, Wainright J L, Kucheryavaya A, Woodbury M, Snyder J J, Kasiske B L, Israni A K
Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN.
Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.
Am J Transplant. 2017 Jan;17 Suppl 1(Suppl 1):21-116. doi: 10.1111/ajt.14124.
The first full year of data after implementation of the new kidney allocation system reveals an increase in deceased donor kidney transplants among black candidates and those with calculated panel-reactive antibodies 98%-100%, but a decrease among candidates aged 65 years or older. Data from 2015 also demonstrate ongoing positive trends in graft and patient survival for both deceased and living donor kidney transplants, but the challenges of a limited supply of kidneys in the setting of increasing demand remain evident. While the total number of patients on the waiting list decreased for the first time in a decade, this was due to a combination of a decrease in the number of candidates added to the list and an increase in the number of candidates removed from the list due to deteriorating medical condition, as well as an increase in total transplants. Deaths on the waiting list remained flat, but this was likely because of an increasing trend toward removing inactive candidates too sick to undergo transplant.
新肾脏分配系统实施后的首个完整数据年份显示,黑人候选者以及计算得出的群体反应性抗体为98%-100%的候选者中, deceased donor肾脏移植数量有所增加,但65岁及以上的候选者中移植数量有所减少。2015年的数据还表明, deceased和活体供肾移植的移植物和患者存活率持续呈积极趋势,但在需求不断增加的情况下,肾脏供应有限的挑战依然明显。虽然等待名单上的患者总数十年来首次下降,但这是由于新增到名单上的候选者数量减少以及因病情恶化从名单上移除的候选者数量增加,再加上移植总数增加所致。等待名单上的死亡人数保持平稳,但这可能是因为将病情过重无法接受移植的非活跃候选者移除的趋势有所增加。