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Systemic Lupus Erythematosus in 2016: Gene expression profiling comes closer to the clinic.

作者信息

Barturen Guillermo, Alarcón-Riquelme Marta E

机构信息

GENYO (Centre for Genomics and Oncological Research), P. T. Ciencias de la Salud, Avenida de la Ilustración 114, 18016 Granada, Spain.

GENYO (Centre for Genomics and Oncological Research), P. T. Ciencias de la Salud, Avenida de la Ilustración 114, 18016 Granada, Spain; and at the Unit for Chronic Inflammatory Diseases, Institute for Environmental Medicine, Karolinska Institutet, 171 67 Stockholm, Sweden.

出版信息

Nat Rev Rheumatol. 2017 Feb;13(2):69-70. doi: 10.1038/nrrheum.2016.211. Epub 2017 Jan 5.

DOI:10.1038/nrrheum.2016.211
PMID:28053330
Abstract
摘要

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Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases.白细胞亚群特异性 1 型干扰素特征在系统性红斑狼疮和其他免疫介导性疾病中的表现。
RMD Open. 2016 May 16;2(1):e000183. doi: 10.1136/rmdopen-2015-000183. eCollection 2016.
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Physiological evidence for diversification of IFNα- and IFNβ-mediated response programs in different autoimmune diseases.
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Arthritis Res Ther. 2016 Feb 17;18:49. doi: 10.1186/s13075-016-0946-9.
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Increased pretreatment serum IFN-β/α ratio predicts non-response to tumour necrosis factor α inhibition in rheumatoid arthritis.治疗前血清干扰素-β/α 比值升高预示类风湿关节炎患者对肿瘤坏死因子α抑制治疗无反应。
Ann Rheum Dis. 2016 Oct;75(10):1757-62. doi: 10.1136/annrheumdis-2015-208001. Epub 2015 Nov 6.
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