系统性红斑狼疮中人类内源性逆转录病毒的转录组分析 - Suppr

Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus.

作者信息

Iñiguez Luis P, de Mulder Rougvie Miguel, Stearrett Nathaniel, Jones Richard B, Ormsby Christopher E, Reyes-Terán Gustavo, Crandall Keith A, Nixon Douglas F, Bendall Matthew L

机构信息

Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10021;

Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10021.

出版信息

Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21350-21351. doi: 10.1073/pnas.1907705116. Epub 2019 Oct 8.

DOI:10.1073/pnas.1907705116

PMID:31594853

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6815141/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16f7/6815141/4cc03e554bbe/pnas.1907705116fig01.jpg

相似文献

Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus.系统性红斑狼疮中人类内源性逆转录病毒的转录组分析

Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21350-21351. doi: 10.1073/pnas.1907705116. Epub 2019 Oct 8.

Cross-talk of the environment with the host genome and the immune system through endogenous retroviruses in systemic lupus erythematosus.系统性红斑狼疮中内源性逆转录病毒介导的环境与宿主基因组和免疫系统的串扰。

Lupus. 2009 Nov;18(13):1136-43. doi: 10.1177/0961203309345728.

DNA methylation modulates HERV-E expression in CD4+ T cells from systemic lupus erythematosus patients.DNA甲基化调节系统性红斑狼疮患者CD4+ T细胞中的HERV-E表达。

J Dermatol Sci. 2015 Feb;77(2):110-6. doi: 10.1016/j.jdermsci.2014.12.004. Epub 2015 Jan 3.

Role of endogenous retroviruses in autoimmune diseases.内源性逆转录病毒在自身免疫性疾病中的作用。

Rheum Dis Clin North Am. 2003 Feb;29(1):123-43, vii. doi: 10.1016/s0889-857x(02)00098-4.

Molecular mimicry between human endogenous retrovirus clone 4-1 and HLA class I antigen with reference to the pathogenesis of systemic lupus erythematosus.

Rheumatology (Oxford). 1999 Nov;38(11):1163-4. doi: 10.1093/rheumatology/38.11.1163.

DNA methylation in systemic lupus erythematosus.系统性红斑狼疮中的DNA甲基化

Lupus. 2003;12(2):79-85. doi: 10.1191/0961203303lu321oa.

[Human endogenous retroviruses and disease?].[人类内源性逆转录病毒与疾病？]

Ugeskr Laeger. 2003 Feb 3;165(6):556-61.

A new hypothesis of the possible mechanisms of gender differences in systemic lupus erythematosus.系统性红斑狼疮中性别差异的可能机制的新假说。

Clin Exp Rheumatol. 2010 May-Jun;28(3):419-23. Epub 2010 Jun 23.

Role of endogenous retroviruses in murine SLE.内源性逆转录病毒在鼠类系统性红斑狼疮中的作用。

Autoimmun Rev. 2010 Nov;10(1):27-34. doi: 10.1016/j.autrev.2010.07.012. Epub 2010 Jul 24.

DNA methylation: its contribution to systemic lupus erythematosus.DNA甲基化：其对系统性红斑狼疮的作用

Clin Exp Med. 2006 Oct;6(3):99-106. doi: 10.1007/s10238-006-0103-x.

引用本文的文献

Shared and unique patterns of autonomous human endogenous retrovirus loci transcriptomes in CD14 + monocytes from individuals with physical trauma or infection with COVID-19.在经历躯体创伤或感染 COVID-19 的个体的 CD14+单核细胞中，自主人内源性逆转录病毒基因座转录组具有共享和独特的模式。

Retrovirology. 2024 Nov 4;21(1):17. doi: 10.1186/s12977-024-00652-z.

: A HERV Turn-On for Autoimmunity, Neurodegeneration, and Cancer?内源性逆转录病毒会引发自身免疫、神经退行性变和癌症吗？

Microorganisms. 2024 Sep 13;12(9):1890. doi: 10.3390/microorganisms12091890.

Integrating human endogenous retroviruses into transcriptome-wide association studies highlights novel risk factors for major psychiatric conditions.将人类内源性逆转录病毒整合到转录组全关联研究中，突出了重大精神疾病的新的风险因素。

Nat Commun. 2024 May 22;15(1):3803. doi: 10.1038/s41467-024-48153-z.

The landscape of hervRNAs transcribed from human endogenous retroviruses across human body sites.人类内源性逆转录病毒在人体不同部位转录的 hervRNA 景观。

Genome Biol. 2022 Nov 3;23(1):231. doi: 10.1186/s13059-022-02804-w.

HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy.人类内源性逆转录病毒特征正常和白血病干细胞，并代表癌症免疫治疗的共享表位的来源。

Am J Hematol. 2022 Sep;97(9):1200-1214. doi: 10.1002/ajh.26647. Epub 2022 Jul 12.

Autoantibodies against the envelope proteins of endogenous retroviruses K102 and K108 in patients with systemic lupus erythematosus correlate with active disease.自身免疫性红斑狼疮患者中针对内源性逆转录病毒 K102 和 K108 包膜蛋白的自身抗体与疾病活动相关。

Clin Exp Rheumatol. 2022 Jul;40(7):1306-1312. doi: 10.55563/clinexprheumatol/2kg1d8. Epub 2021 Oct 13.

Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression.人类内源性逆转录病毒在系统性红斑狼疮中的表达：与基因表达的多组学整合。

Front Immunol. 2021 Apr 27;12:661437. doi: 10.3389/fimmu.2021.661437. eCollection 2021.

How Retroviruses and Retrotransposons in Our Genome May Contribute to Autoimmunity in Rheumatological Conditions.我们基因组中的逆转录病毒和逆转座子如何导致风湿性疾病中的自身免疫。

Front Immunol. 2020 Nov 13;11:593891. doi: 10.3389/fimmu.2020.593891. eCollection 2020.

Human Endogenous Retrovirus Expression Is Upregulated in the Breast Cancer Microenvironment of HIV Infected Women: A Pilot Study.人类内源性逆转录病毒在HIV感染女性乳腺癌微环境中表达上调：一项初步研究。

Front Oncol. 2020 Oct 22;10:553983. doi: 10.3389/fonc.2020.553983. eCollection 2020.

Reply to Iñiguez et al.: ERVmap is a validated approach to mapping proviral endogenous retroviruses in the human genome.回复伊尼格斯等人：ERVmap是一种经过验证的在人类基因组中绘制前病毒内源性逆转录病毒图谱的方法。

Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21352-21353. doi: 10.1073/pnas.1908504116. Epub 2019 Oct 8.

本文引用的文献

Telescope: Characterization of the retrotranscriptome by accurate estimation of transposable element expression.望远镜：通过准确估计转座元件的表达来对逆转录组进行特征描述。

PLoS Comput Biol. 2019 Sep 30;15(9):e1006453. doi: 10.1371/journal.pcbi.1006453. eCollection 2019 Sep.

ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses.ERVmap 分析揭示了人类内源性逆转录病毒的全基因组转录。

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12565-12572. doi: 10.1073/pnas.1814589115. Epub 2018 Nov 19.

A survey of best practices for RNA-seq data analysis.RNA测序数据分析的最佳实践调查。

Genome Biol. 2016 Jan 26;17:13. doi: 10.1186/s13059-016-0881-8.

TEtranscripts: a package for including transposable elements in differential expression analysis of RNA-seq datasets.TE转录本：一个用于在RNA测序数据集差异表达分析中纳入转座元件的软件包。

Bioinformatics. 2015 Nov 15;31(22):3593-9. doi: 10.1093/bioinformatics/btv422. Epub 2015 Jul 23.

A comprehensive evaluation of ensembl, RefSeq, and UCSC annotations in the context of RNA-seq read mapping and gene quantification.在RNA测序读段映射和基因定量的背景下，对Ensembl、RefSeq和UCSC注释进行全面评估。

BMC Genomics. 2015 Feb 18;16(1):97. doi: 10.1186/s12864-015-1308-8.

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.使用DESeq2对RNA测序数据的倍数变化和离散度进行适度估计。

Genome Biol. 2014;15(12):550. doi: 10.1186/s13059-014-0550-8.

Transcriptional landscape of repetitive elements in normal and cancer human cells.正常和癌症人类细胞中重复元件的转录图谱。

BMC Genomics. 2014 Jul 11;15:583. doi: 10.1186/1471-2164-15-583.

Repetitive DNA and next-generation sequencing: computational challenges and solutions.重复 DNA 和新一代测序：计算挑战与解决方案。

Nat Rev Genet. 2011 Nov 29;13(1):36-46. doi: 10.1038/nrg3117.

RNA-Seq gene expression estimation with read mapping uncertainty.基于读段比对不确定性的 RNA-Seq 基因表达估计。

Bioinformatics. 2010 Feb 15;26(4):493-500. doi: 10.1093/bioinformatics/btp692. Epub 2009 Dec 18.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献