Pal C P, Kumar Harendra, Kumar Deepak, Mittal Vivek, Deshwar Gaurav, Altaf Danish, Verma Sushant
Department of Orthopaedics, S.N. Medical College, Agra, Uttar Pradesh, India.
Department of Pathology, S.N. Medical College, Agra, Uttar Pradesh, India.
J Clin Orthop Trauma. 2016 Oct-Dec;7(Suppl 2):143-146. doi: 10.1016/j.jcot.2016.06.009. Epub 2016 Oct 15.
Many recent reports demonstrated high rates of vitamin D deficiency in numerous segments of Indian population but no study has been reported so far from India, which focuses specifically on vitamin D status in orthopaedic patients. This study finds out the prevalence of vitamin D deficiency in orthopaedic patients in India.
Vitamin D levels of 1132 patients were measured from OPD and Emergency Department of S.N. Medical College, Agra from 1 November 2011 to 31 October 2013. Serum 25(OH) vitamin D, calcium, phosphorus, alkaline phosphatase and routine blood investigations were done. BMI and daily sun exposure were measured.
Out of 1132 patients included in our study, 732 (64.7%) were males and 400 (36.3%) females. Vitamin D deficiency (<30 ng/ml) was present in 1034 patients (91.3%); among them, 693 patients (61.2%) had vitamin D level <20 ng/ml and only 98 patients (8.7%) had sufficient levels of vitamin D. Vitamin D deficiency was more in elderly patients (61-80) than in younger patients. Among 1132 patients, 670 males (91.5%) and 364 females (91.0%) were found to have serum 25(OH) vitamin D levels <30 ng/dl cut-off for vitamin D sufficiency (-value = 0.75). Vitamin D levels were lower in patients with less mean sun exposure time. BMI level was more in deficient group than the sufficient group relatively.
High incidence of vitamin D insufficiency and deficiency likely exists across all age groups among orthopaedic patients. Screening and treating hypovitaminosis D appears to be important in this patient population.
近期许多报告显示，印度众多人群中维生素D缺乏率很高，但迄今为止，印度尚未有专门针对骨科患者维生素D状况的研究报告。本研究旨在查明印度骨科患者维生素D缺乏的患病率。
对2011年11月1日至2013年10月31日期间在阿格拉S.N.医学院门诊部和急诊科的1132例患者测定维生素D水平。检测血清25(OH)维生素D、钙、磷、碱性磷酸酶并进行常规血液检查。测量体重指数（BMI）和每日日照时间。
在纳入本研究的1132例患者中，男性732例（64.7%），女性400例（36.3%）。1034例患者（91.3%）存在维生素D缺乏（<30 ng/ml）；其中，693例患者（61.2%）维生素D水平<20 ng/ml，仅有98例患者（8.7%）维生素D水平充足。老年患者（61 - 80岁）的维生素D缺乏情况比年轻患者更严重。在1132例患者中，发现670例男性（91.5%）和364例女性（91.0%）的血清25(OH)维生素D水平低于维生素D充足的临界值30 ng/dl（P值 = 0.75）。平均日照时间较短的患者维生素D水平较低。缺乏组的BMI水平相对高于充足组。
骨科患者各年龄组中维生素D不足和缺乏的发生率可能都很高。对维生素D缺乏症进行筛查和治疗在这类患者群体中似乎很重要。
