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直立性低氧血症综合征:脊髓损伤中房间隔缺损的一种罕见并发症。

Orthodeoxia syndrome: a rare complication of ASD in spinal cord injury.

作者信息

Magimairaj H, Hariharan R, Thumbikat P

机构信息

The Princess Royal Spine Injuries Center, Northern General Hospital , Sheffield, UK.

出版信息

Spinal Cord Ser Cases. 2015 Jul 9;1:15005. doi: 10.1038/scsandc.2015.5. eCollection 2015.

Abstract

STUDY DESIGN

This is a single-subject case report.

OBJECTIVES

The objective is to describe and discuss a rare presentation of orthodeoxia after spinal cord injury in a previously healthy adult with an asymptomatic and undiagnosed atrial septal defect.

SETTING

This study was conducted at the Tertiary Care Spinal Injuries Center in Sheffield, UK.

METHODS

An 81-year-old woman who was otherwise healthy and active sustained a polytrauma following a road traffic collision. Her injuries were managed conservatively. As a complication of epidural analgesia, she developed a complete thoracic paraplegia secondary to an epidural hematoma. She was found to have repeated episodes of severe deoxemia, without any significant postural hypotension when attempts were made to sit her up in bed. Detailed investigations were done to ascertain the cause for this deoxemia.

RESULTS

Echocardiography revealed an atrial septal defect; agitated saline contrast transesophageal ultrasound done in various positions revealed interatrial defect with reversal of shunting when the patient was made to sit up in bed.

CONCLUSION

Orthodeoxia is an uncommon finding in spinal injury patients. Detailed investigations at an early stage of rehabilitation need to be done to rule out cardiac causes after ruling out the common medical complications seen in the acute and subacute phases following spinal cord injury.

摘要

研究设计

这是一篇单病例报告。

目的

描述并讨论一名既往健康的成年人在脊髓损伤后出现的罕见的直立性低氧血症表现,该患者患有无症状且未被诊断出的房间隔缺损。

背景

本研究在英国谢菲尔德的三级护理脊髓损伤中心进行。

方法

一名81岁、原本健康且活跃的女性在道路交通事故后遭受了多处创伤。她的损伤采用保守治疗。作为硬膜外镇痛的并发症,她因硬膜外血肿继发了完全性胸段截瘫。在尝试让她在床上坐起时,发现她反复出现严重低氧血症,且无明显体位性低血压。进行了详细检查以确定这种低氧血症的原因。

结果

超声心动图显示存在房间隔缺损;在不同体位进行的经食管超声心动图造影检查显示,当患者在床上坐起时,房间隔缺损处出现分流逆转。

结论

直立性低氧血症在脊髓损伤患者中并不常见。在脊髓损伤后的急性期和亚急性期排除常见的医学并发症后,康复早期需要进行详细检查以排除心脏原因。

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