结肠癌脊髓髓内转移：19例报告病例分析
Intramedullary spinal cord metastasis from colon cancer: analysis of 19 reported cases.
作者信息
Tsai Tai-Hsin, Lin I-Cheng, Lin Pei-Chen, Wu Chieh-Hsin, Lin Chih-Lung, Su Yu-Feng
机构信息
Department of Neurosurgery, Kaohsiung MedicalUniversity Hospital, Kaohsiung, Taiwan; Graduate Institute of Medicine and Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Department of Neurosurgery, Kaohsiung Medical University Hospital , Kaohsiung, Taiwan.
出版信息
Spinal Cord Ser Cases. 2016 Jan 7;2:15026. doi: 10.1038/scsandc.2015.26. eCollection 2016.
We report and analyze a rare entity of intramedullary spinal cord tumor, which is metastatic from colon cancer with a very poor prognosis. The reported 19 cases including our case in the literature are analyzed. Comparison of outcomes between surgery, radiotherapy and non-treatment groups are evaluated. Life distribution is profiled. Median overall survival is 75 days. The 90 days and 150 days survival rate are 42.9% and 21.4%, respectively. There were no differences between conservative treatment (non-treatment or radiotherapy) and aggressive intervention (surgery or surgery plus radiotherapy) in mortality and the trend of survival probability. The prognosis of metastatic intramedullary spinal cord tumor is poor. Surgery may only be considered in selected patients with good control of primary cancer and without evidence of lung metastases and leptomeningeal carcinomatosis.
我们报告并分析了一种罕见的脊髓髓内肿瘤，它是结肠癌转移所致，预后极差。对文献中报道的包括我们病例在内的19例病例进行了分析。评估了手术、放疗和未治疗组之间的预后比较。分析了生存分布情况。中位总生存期为75天。90天和150天生存率分别为42.9%和21.4%。在死亡率和生存概率趋势方面，保守治疗（未治疗或放疗）与积极干预（手术或手术加放疗）之间没有差异。转移性脊髓髓内肿瘤的预后很差。仅在原发癌得到良好控制且无肺转移和软脑膜癌转移证据的特定患者中才考虑手术。
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